Following a walk to Dustin Ackley, Jackson wound up scoring from second on a Robinson Cano single to give Seattle a four-run lead. It was Jackson's 19th stolen base of the season and 10th since he was acquired from the Tigers in a July 31 trade.
McClendon has challenged 31 plays this season and had 17 overturned.
The Astros were unsuccessful in a challenge of their own in the eighth inning. With one out and runners on second and third, Jake Marisnick hit a grounder to Seattle third baseman Kyle Seager, and Marisnick was called out on the close play.
Astros interim manager Tom Lawless challenged, but the call stood. Marisnick's groundout capped a 2-for-4 night for his second consecutive multihit game.
Greg Johns and Brian McTaggart are reporters for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.