As for those streaks ...
• First, the Padres' five-game winning streak, their longest since June 10-17 of last season, is gone. The Padres were three outs away from making it 6-for-6 but couldn't quite finish the Giants.
• The Padres entered the game with a 32-0 record in games in which they led after eight innings, a testament, in large part, to the work of relievers Joaquin Benoit and closer Huston Street.
"They have had a great run. You play 162 [games] and you're not going to be invincible," said San Diego manager Bud Black. "They've been so good for so long. Today, a couple guys got nicked."
• Street, who entered the game having converted all 23 of his save opportunities this season, allowed a game-tying home run to Michael Morse in the ninth inning.
"I'm obviously frustrated for the team, because we had the win in hand if I made a good pitch. I didn't and it's really nothing more than that. ... Don't hang a slider next time," Street said.
But for all that went wrong for the Padres (39-48), they did a few things right Saturday. Like in the ninth inning as they nearly won it when Chase Headley doubled and moved to third base on a ground ball. A nice play by shortstop Brandon Crawford prevented Headley from scoring.
Sergio Romo intentionally walked Jake Goebbert but Cameron Maybin popped up to the infield for the second out. Pinch-hitter Carlos Quentin then struck out to end the inning.
Two innings earlier, Goebbert (RBI triple) and Maybin (sacrifice fly) gave the Padres a 3-2 lead against Giants reliever Jean Machi, who entered the game with a 1.29 ERA.
"I felt we pieced together some good at-bats the whole game but finally broke through facing Machi," Goebbert said.
In his first start against the Giants on June 23, which happened to be his first big league start, Odrisamer Despaigne got 11 ground-ball outs and needed only 86 pitches to cover seven scoreless innings.
The Padres rookie labored more Saturday, as his command wasn't nearly as sharp. He was behind in the count, and he walked four in six innings, needing 103 pitches to get through six innings.
"This guy knows his game. The last game [against the Giants], he was more aggressive with his fastball. Tonight, he wasn't pinpoint with it. But he worked his way out of jams. The Giants had some funky swings at times," Black said.
That said, Despaigne allowed one run -- a home run to Gregor Blanco, a 423-foot bolt into the right-field seats in the second inning -- on two hits.
"I think he was trying to be more perfect with his pitches," said Padres catcher Yasmani Grandal. "As he goes along, he'll learn a little bit more how to use that fastball."
In the last six games, including five victories, Padres starting pitchers have a combined 0.68 ERA.
San Francisco starting pitcher Tim Hudson was equally as stingy, as his sinker had plenty of movement. Hudson retired 11 consecutive hitters at one point until Brooks Conrad singled to start the sixth inning.
Conrad then moved to third base on Alexi Amarista's single to right field. Hudson righted himself with a strikeout of pinch-hitter Tommy Medica but allowed a sacrifice fly to Seth Smith to tie the game.
The Giants (48-39) tied the game with a run in the seventh inning on two walks -- issued by reliever Alex Torres -- and a balk and a sacrifice fly against rookie reliever Kevin Quackenbush, setting the stage for a wild last few innings.