It looked as though the Mets would take the defeat an inning earlier after Harrison reached third base with no outs in a nutty-and-controversial rundown where he wasn't tagged out or called out of the basepath. Harrison led off the 10th with a single and stole second, with the Mets losing a challenge after the steal. However, right-handed reliever Jenrry Mejia struck out Travis Snider and Neil Walker, with an intentional walk of Andrew McCutchen in between, and then got Russell Martin to fly out to right and extend the game.
Even with the new life, the Mets came up empty in the 11th and lost in the home half of the frame to fall to 36-44 on the season.
"Any loss is going to be tough," second baseman Daniel Murphy said. "Mejia did a great job right there that inning. It's a loss. Losses are tough. I don't know any other way to describe it."
Without Wright -- who will undergo an MRI in New York on Saturday -- the Mets scored just two runs for the second consecutive game, both of which came on a Lucas Duda single in the fourth inning. It was the third game in a row the first baseman had an RBI, and Duda has driven in eight runs in his last five games.
The Pirates tied the game in the bottom of the fourth when Jordy Mercer hit a two-run single off Mets starter Jacob deGrom with two outs, but both teams were then scoreless until Harrison's two-bagger to right center ended it.
The Mets did have a few chances to push the go-ahead run across. In the fifth, Juan Lagares and Travis d'Arnaud led off the inning with back-to-back singles, but no runner even made it to third. In the ninth against Pirates closer Mark Melancon, the Mets had runners on the corners for pinch-hitter Bobby Abreu, who grounded out to end the threat.
The Pirates' bullpen tossed four scoreless frames, but the Mets were also limited by starter Brandon Cumpton, who went seven innings and struck out four.
"He's got that two-seamer that he runs in to lefties," Murphy said of what made Cumpton challenging. "…We had some traffic out there, hit some balls hard, and Jake threw the ball well. I thought we hit the ball hard tonight, thought we had some good at-bats."
Cumpton's counterpart, deGrom, had a nearly similar line in the box score, and also was hurt by just one swing of the bat. Before Mercer stepped to the plate in the fourth, Martin hit a sharp ground ball to Duda, who bobbled it for a second and was unable to get to the base before Martin. deGrom thought Duda had it cleanly and didn't cover first in time, which may have cost him a run.
"When he dove, I thought he had it," deGrom said. "And I looked toward second to see if he was going to make the throw, and I didn't see the ball roll out. I was frustrated I wasn't over there."
Even with the shaky fourth inning, deGrom had his second quality start in a row. The lanky right-hander went 6 2/3 innings, surrendered five hits, struck out four and walked three.
"[He] threw the ball very well today, he really did," Mets manager Terry Collins said of deGrom. "Made pitches, velocity was up. It was impressive."