"I just didn't want to take a chance of running him out there in this big field and making something that small worse than it was," manager Fredi Gonzalez said.
Upton moved through the clubhouse after the game in relatively normal fashion, and he hopes to return to the lineup by the time this four-game series concludes on Thursday.
"I don't know how I'm going to feel tomorrow," Upton said, "but I'm optimistic that it's not anything too serious."
Mark Bowman is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.