Blue Jays right fielder Jose Bautista tracked the ball toward the stands about halfway down the line, and he seemed to have a clear angle to make the out.
But the outstretched hand of a young fan collided with Bautista's glove, allowing the ball to drop to the ground -- the play was ruled a foul ball.
After a review of one minute, 43 seconds, the call was overturned, and Cruz was ruled out. Janssen went on to retire Matt Carpenter to secure the win for the Blue Jays.
Jamie Ross is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.