Dominguez doubled twice and drove in four runs Friday to lead the Mesa Solar Sox to their third straight win, an 11-1 rout of the Surprise Rafters.
The former first-round pick delivered an RBI double and scored in Mesa's four-run second inning, walked and scored again in a three-run third, then capped a three-run fourth with a two-run double.
Dominguez, who lifted a sacrifice fly in the sixth, credited his improved mechanics, something he's been working on during his time in the Arizona Fall League.
"I'm up there trying to be patient and get a good pitch to hit," he said. "Just get a good pitch and put the barrel on it."
The 20-year-old third baseman broke out of a 1-for-21 slump with a two-run homer in Wednesday's 8-5 victory over the Peoria Javelinas. He'll represent the Marlins on Saturday in the AFL Rising Stars Showcase, a game loaded with top prospects.
"I was pretty excited, it's a pretty big deal," said Dominguez, who was a Florida State League All-Star this season. "The baseball here is pretty good and this is quite an honor. It should be fun playing in it."
Red Sox infield prospect Jose Iglesias homered and drove in five runs as part of Mesa's 16-hit attack. Hank Conger (Angels) doubled, singled and scored three times, while Bryan Petersen (Marlins) contributed three hits.
Steve Hirschfeld (1-2) allowed one hit and struck out two over three shutout innings for the win. Fellow Twins prospect Spencer Steedley pitched two scoreless, giving up two hits and fanning two.
Royals prospect Mike Moustakas, the second overall pick in the 2007 Draft, homered in the ninth to produce the Rafters' lone run. Reese Havens (Mets) had a pair of hits for Surprise, which has lost two in a row.
Blake Wood (Royals) took the loss after surrendering four runs on five hits in 1 1/3 innings. Cardinals Minor Leaguer Adam Reifer pitched a perfect frame out of the bullpen and has not allowed a run in his last five appearances.
Robert Emrich is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.