Crisp immediately fell to the ground following the catch and remained there for nearly five minutes, before standing and walking slowly off the field with head trainer Nick Paparesta.
Crisp headed straight for the clubhouse and was replaced in the bottom of the inning by Craig Gentry.
The A's lost the opener, 6-4, but bounced back in the nightcap with a 2-0 win.
Jane Lee is a reporter for MLB.com. Read her blog, Major Lee-ague, and follow her on Twitter @JaneMLB. This story was not subject to the approval of Major League Baseball or its clubs.