After the starting lineups are announced, members of the Northwestern University marching band will take the field, which was customary for Opening Day and other special events during the ballpark's first two decades.
Major League Baseball Commissioner Bud Selig will attend as well as past and present team owners. The Chicago Bears, who played 50 seasons at Wrigley Field from 1921-70, also will be honored.
Before the game, Cubs alum will take the field, including Ernie Banks, Glenn Beckert, Andre Dawson, Ryan Dempster, Bobby Dernier, Randy Hundley, Fergie Jenkins, Gary Matthews, Milt Pappas, Lee Smith, Billy Williams, Kerry Wood, and Sam and Spencer Brown (grandchildren of Ron Santo).
• Wednesday's game will be the eighth time the Cubs will wear throwback uniforms in a regular-season game, and first of 10 such instances this year. Chicago is 6-1 so far in the retro uniforms. On Wednesday, the Cubs will wear versions of the Chicago Federals' uniforms.
Carrie Muskat is a reporter for MLB.com. She writes a blog, Muskat Ramblings, and you can follow her on Twitter @CarrieMuskat. This story was not subject to the approval of Major League Baseball or its clubs.