It's been more than four months since the Red Sox and Cardinals faced each other for all the marbles. On Wednesday, the two World Series clubs will square off live on MLB.TV at 1:05 ET for the first time since Boston won Game 6.
Left-hander Chris Capuano will make his Red Sox debut, and top prospect Anthony Ranaudo, who was dominant in his first Grapefruit League start, also is scheduled to pitch. Shelby Miller gets the call for the Cardinals in his first start of the spring.
With all 30 Major League clubs in action, it's just one of many interesting matchups on Wednesday's slate.
Jayson Werth is set to make his spring debut when the Nationals face the Mets for a 1:05 ET contest that can be heard live on Gameday Audio. Gio Gonzalez also will make his first start of the Grapefruit League season.
Though Werth missed the first five games with a right biceps strain, Washington manager Matt Williams said Tuesday that the outfielder is "good to go."
Keeping it in the National League East, Braves right-hander Brandon Beachy gets the call against the Phillies in his second start of the spring. The game can be seen live on MLB.TV at 1:05 ET. Beachy is continuing to distance himself from elbow issues that limited him to just five starts last season.
"I'm just going to keep going out there and do what the training staff tells me to do," Beachy said. "I feel pretty confident in the way I've been feeling and the way I'm going to feel. I've got April and October in mind and not today."
Jose Fernandez, who recently was named the Marlins' Opening Day starter, will face the Mets in his second Grapefruit League start at 1:10 ET live on MLB.TV. Right-hander Dillon Gee will make his first start for New York.
Reigning American League Cy Young Award winner Max Scherzer will get the start as the Tigers head to Kissimmee, Fla., to face the Astros at 1:05 ET live on MLB.TV. Scherzer gave up one run on one hit and struck out two in his first outing Friday against the Yankees. Ian Kinsler is expected to bat leadoff, with Victor Martinez hitting third and Alex Avila batting fourth.
Two staff aces will face off in a Cactus League matchup between the Angels and Giants. Jered Weaver will make his second start of the spring opposite right-hander Matt Cain, who will make his spring debut because of a rainout Saturday. The game can be seen live on MLB.TV at 3:05 ET.
Weaver pitched three scoreless innings against the Cubs in his spring debut, giving up one hit. Weaver faced the minimum in the first two innings, then notched a 1-2-3 third to finish his day.
"Obviously, that first start, you're a little nervous going into it, just because you don't know if location is going to be there or whatnot, but I felt good," Weaver said after the game. "I don't know how many pitches I threw, but I still felt like I had some more to go."
In the final game of the day, the Dodgers will travel to Goodyear, Ariz., to face the Reds live on MLB.TV at 9:05 ET. Hyun-Jin Ryu gets the nod for the Dodgers, while Homer Bailey will make his second start of the spring. Los Angeles manager Don Mattingly said Dee Gordon will get his first spring start in center field.
Quinn Roberts is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.