The Angels did bring lefty starter C.J. Wilson to Peoria Stadium, and he struck out the side in the first, getting Cano looking for the final out. Wilson, slated to be the Angels' No. 2 starter this season, allowed three runs on three hits with a walk and four strikeouts in two-plus innings.
The Mariners got to Wilson for pair of runs in the second after Justin Smoak led off the frame with a towering double off the center-field batter's eye. Wilson was replaced by Michael Morin after a leadoff single by Mariners right fielder Xavier Avery in the third, and Avery eventually came around to score as Seattle pushed across two more runs to make it 4-0.
"The sliders today, they didn't really swing at it, which was kind of weird," Wilson said. "They took all of them. That's why I got them to strike out with the fastball. It's kind of a cat-and-mouse thing, because you're like, 'Oh, I'm going to throw them this way during the season so I shouldn't throw them that way now. I should do something different so I save that.' But you start thinking about that type of stuff and you end up throwing a meatball."
Cano had his RBI single in the third and Dustin Ackley followed with a run-scoring double, his second in as many games this spring. Cano, who signed a 10-year, $240 million contract in December, finished 2-for-3 with a pair of singles and is now 3-for-4 with a walk in two games.
Baker, who pitched just three games for the Cubs last September after having Tommy John surgery in 2012, said he felt strong while throwing 32 pitches in his first outing of the spring. He'll have a good chance to crack the Mariners' rotation as a non-roster invitee if he proves healthy over the next month.
"I feel good," said the former Twins starter. "It's that two-year mark [after surgery]. You keep hearing it and hearing it. I'm coming up on that and now that I have experienced it, I see there's a reason people talk about that. I feel like I'm able to go out there and let the ball fly without any adverse affects, and that's a good feeling."
Smoak and designated hitter Logan Morrison each had two hits, including a double apiece, for the Mariners.
The Angels got on the board with an RBI double by shortstop Tommy Field in the sixth off James Gillheeney, and C.J. Cron followed with a sacrifice fly to make it 5-2.
Up next: Angels fans will get their first look at Hector Santiago on Sunday, when the 26-year-old left-hander faces off against A's righty Jesse Chavez at Tempe Diablo Stadium. Santiago, acquired as part of the three-team deal that sent Mark Trumbo to Arizona in December, posted a 3.56 ERA in 149 innings with the White Sox last season and will be looking to throw his nasty screwball more often this spring. Most of the Angels' everyday players should be in the lineup after taking Saturday off. Game time is 12:10 p.m. PT and is available on MLB.TV.