Owings came out with tightness in his right shoulder after surrendering two runs in three innings. Owings walked four and gave up three hits, walking in a run during a 33-pitch second and allowing an RBI double to Alfonso Soriano in the third.
"As the game went on, it got stiffer and stiffer, tighter and tighter," Owings said. "I was missing some pitches a foot-and-a-half off the plate, and I've done that here and there over the course of the year, but more and more lately, and that's just not me."
Manager Dusty Baker replaced Owings with Carlos Fisher to start the fourth. Owings will be examined Monday in Cincinnati by Reds medical director Dr. Timothy Kremchek.
"It's the hardest thing I've ever had to do, taking myself out of the game, but I wasn't going to be helping the team," Owings said.
Dickerson was hurt in the eighth, when Koyie Hill hit a fly ball into right-center. Dickerson ran into the gap and made a full-out, diving attempt, but the ball went off his glove.
Dickerson stayed down for a moment but then got up and left the game with a jammed left shoulder. He said he did not believe the injury was as serious as the torn rotator cuff he suffered in 2006 on a similar play. He was more concerned that he missed the ball, allowing Hill to get an RBI triple that put the Cubs ahead, 4-1.
"When the ball goes off your glove like that, it's the worst feeling," Dickerson said. "Key point in the game right there to keep us close, and to get a beat on the ball and have it go off your glove like that, it's just one of those things."
Dickerson will have an MRI on Monday in Cincinnati.
The Reds already have seven players on the disabled list, including outfielder Jay Bruce, catcher Ramon Hernandez and starting pitcher Edinson Volquez. With the team 7 1/2 games out of first place, they cannot afford to have any more guys go down.
"We don't have a superstar like Albert Pujols on our team or somebody like that, so we need all 25 guys," utility man Jerry Hairston Jr. said. "When guys get hurt, it definitely puts a strain on our team. That being said, we can't use that as an excuse. We have to go out there and play, and play well."
Andrew Simon is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.