Francona and Jason Varitek, were ejected in the seventh inning of an eventual 3-1 Boston win over the Twins for arguing with home-plate umpire Todd Tichenor about a pitch by Josh Beckett that was called a ball.
In the top of the inning, Twins manager Ron Gardenhire and catcher Mike Redmond were ejected, also by Tichenor, for disputing a close play at the plate in which Boston baserunner Jeff Bailey was called safe.
According to the Herald, Francona was pacing in his office, agitated and "worked up" because of the ejections of himself and Varitek when a member of the Red Sox training staff suggested that Francona, who has a history of medical issues, be examined before the team left the Metrodome to bus to the airport and then fly to Toronto, where a three-game series is to begin on Friday.
Several EMTs, including one with a stretcher and emergency equipment, entered the clubhouse as the team was preparing to leave and two of them stood outside the trainer's room, directing players away as Francona was examined inside the room, according to the Herald.
After the examination, Francona headed for the bus with media relations director Pam Ganley.
"I'm fine," Francona said. "I just got a little worked up and my blood pressure shot up. But I'm fine. They take good care of me."
Francona, 50 and in his 10th season as a Major League manager and sixth with the Red Sox, has had medical scares in the past.
He was taken to a hospital in April 2005 after sweating profusely and complaining of chest pains while riding the team bus from Manhattan to Yankee Stadium. The symptoms were determined to be caused by a virus.
Francona was hospitalized for 10 days in 2002 because of blood clots in his lungs, and complications from knee surgeries later that year caused bleeding in the artery in his right thigh and nearly led to an amputation. As a result, he takes blood-thinning medication daily.
Bobbie Dittmeier is an editor/producer for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.