No makeup date was set, but the teams do have a mutual off-day June 24.
Jackson's last start last Thursday in Pittsburgh also was interrupted by rain, but he had given up four runs over three innings when nature intervened.
"It's just one of those things," Jackson said. "Sometimes when you have a season like I'm having, that's how it is. You feel good and something happens, and you feel bad and something happens. It's kind of awkward -- back-to-back rainouts. That might be a first."
The intracity Interleague series isn't over. The two teams have two more games at Wrigley Field on Wednesday and Thursday.
The Cubs hated to waste any offense against left-handed starters. They've struggled this season, even though they scored four quick runs off White Sox starter Jose Quintana on Monday en route to a 7-0 victory.
"Those are things you hopefully build on and get hot and everybody gets hot at the same time," Cubs manager Dale Sveum said prior to Tuesday's game.
The trouble is, they were facing a different lefty in Game 2 in Chris Sale.
"That kind of stuff and that arm angle is something you don't see on an everyday basis," Sveum said of Sale. "You don't see the velocity, you don't see the ball coming from that area. ... He's more of a power-pitching specialist, and he's out there pitching seven, eight, nine innings."
Sale needed just eight pitches to get through the first inning, but with one out in the second, Scott Hairston doubled to left. Castillo followed with his second homer of the season on an 0-1 pitch. If it had counted, the homer would've ended Sale's scoreless-innings streak at 24.
"You hate to waste any time you get up 2-0 against a pitcher like Sale," Sveum said. "You score two and hopefully a couple more and you've done your share off a guy like that. It's too bad the game has to get canceled that quick. We knew that rain was coming."
Castillo could only laugh at losing the home run.
"I hit a slider," Castillo said. "I tried to get a good at-bat and be aggressive. I know he's not easy to hit. I just didn't put too many things in my head, just see the ball and swing. He made a good pitch. Sometimes you've got to be lucky."
Jackson could only shrug. After his last start, Sveum talked about how the right-hander needed to pitch with more "conviction." He did just that.
"He came out throwing the ball really well, obviously with a lot of conviction and had velocity from the get-go," Sveum said. "That's how we want the guy to go out there all the time."