Indians right-hander Zach McAllister -- lined up to be his team's fourth starter this season -- pitched into the sixth inning and surrendered five runs, including two on Cespedes' two-run homer in the fifth. It marked McAllister's final Cactus League appearance before the start of the regular season.
"I felt like delivery-wise I felt really good," McAllister said. "I felt like I had good life on my fastball today. For the most part, I think it went well -- except for that curveball to Cespedes. He's a really good hitter. I want to be aggressive. I don't want to give up runs. I know I have to attack him. That one was just a little too good of a pitch for him to hit."
McAllister ended the afternoon with two walks, three strikeouts and eight hits allowed in 5 2/3 innings.
"He had good life on his fastball," Indians manager Terry Francona said. "It took him three innings to find his breaking ball. He got hurt with it a couple of times, but as he got into the game, he started throwing it better."
Anderson, who is in line to start Oakland's opener, yielded three runs (two earned) on six hits in 5 1/3 innings. The left-hander had one strikeout and one walk in his fourth Cactus League appearance of Spring Training. In the fourth inning, Anderson allowed a solo home run to Cleveland utility man Ryan Raburn, who will begin this year on the Tribe's bench.
The Indians struck for one run in the first inning, when Mike Aviles tripled and later crossed the plate on a sacrifice fly from Carlos Santana. An inning later, Indians second base prospect Jose Ramirez contributed an RBI single. He also drove in one of the team's two runs in the ninth. The other ninth-inning run scored on a wild pitch.
In the first inning, Josh Reddick came through with a triple against McAllister, who then allowed Oakland's right fielder to score from third base on a wild pitch. Brandon Moss later added a run-scoring double that pushed the A's to a 2-0 lead.
Cespedes' blast in the fifth inning highlighted a three-run outburst for the A's.
Indians All-Star closer Chris Perez worked a scoreless seventh inning in his first Cactus League game since injuring his right shoulder in an outing on Feb. 26. Perez struck out Michael Choice and later induced an inning-ending double play grounder off the bat of Hiroyuki Nakajima.
"I felt normal," Perez said. "Like I told you guys before, the injury is gone. Now it's just trying to get caught up to speed with location and putting guys away."
Francona also seemed pleased with his closer's scoreless outing.
"He was good," Francona said. "He felt good. He said he felt a little rusty, but he didn't look like that. He was free and easy and letting it fly. I thought the ball came out of his hand really well. ... He lets it fly. I thought he looked really good. That was probably the highlight of the day."
Up next: Many of Cleveland's regulars will make the trip to Camelback Ranch on Wednesday, when the Indians and White Sox meet in a 3:05 p.m. ET Cactus League contest. Three of the Tribe's offseason acquisitions -- first baseman Nick Swisher, center fielder Michael Bourn and designated hitter Mark Reynolds -- are slated to be on hand for the road game. Right-hander Daisuke Matsuzaka is penciled in as the starter for the Indians, with setup man Vinnie Pestano among the relievers scheduled to appear. The game will be televised on MLB Network and a live webcast will be available on Indians.com.