Germano (2-5) took the loss, giving up five runs over five innings in a game which was in doubt due to rain from Hurricane Isaac.
The Giants loaded the bases with two outs in the first and Germano hit Hector Sanchez with a pitch, although the ball just grazed his jersey. Nady, among the Giants' September callups, then doubled down the left-field line to take a 4-0 lead. It was his first multi-RBI game since July 27, 2011.
"He's a good hitter," Germano said of Nady. "You definitely have to mix it up with him. He can hurt you with a long ball and drive the ball in the gap. I tried to get a fastball in there and tried to get a ground ball, and I did, but he was able to keep it out of reach of [third baseman Luis] Valbuena."
How was Nady, the roommate?
"He was clean, he was funny," Germano said. "He kept us all in a good mood. He was definitely a good guy to have on the team, and as a roommate."
The two roomed with infielder J.J. Furmaniak and pitcher Dennis Tankersley that season.
"I think [Nady] could probably find something to say to pick things up," Germano said. "He was always good at that."
Nady was just happy to be in a big league lineup, even if he was wearing No. 68.
"I always wanted to put on a Giants uniform," said Nady, who was a Will Clark fan. "To have the opportunity to do it, I knew going to [Triple-A] Fresno could benefit me."
The Giants added another run in the second on Marco Scutaro's sacrifice fly, scoring Angel Pagan, who tripled.
All of that offense had to be a surprise for Lincecum (8-14), who entered the game with the fifth-lowest run support in the National League this year. Lincecum didn't exactly look like a two-time Cy Young winner, but got the job done, holding the Cubs to four hits over 6 1/3 innings, and picked up his first win against them since May 5, 2009.
"I think he'll tell you that's not the guy we saw winning Cy Youngs and having the command and velocity of the fastball -- all of that is completely different than it was a few years ago," Cubs manager Dale Sveum said. "He knows how to get through lineups with his offspeed stuff and his changeup and curveball."
David DeJesus was the Cubs' star both on offense and defense. He closed the gap to 5-2 in the Cubs' third when he hit a two-run home run, his seventh of the season. DeJesus also made the catch of the game when he robbed Buster Posey of a possible extra-base hit with a sliding grab along the right-field line in the fifth.
"I didn't even know I caught it, to be honest with you," DeJesus said. "I slid and threw my glove out, and I was lifting my glove up and I didn't expect the ball to be in there. I said, 'Wow, it's in there, this is pretty cool.'"
Fortunately for the Cubs, he didn't say that anything hurt after his slide. Sveum is hoping the young players on the Cubs roster -- and there are many -- pay attention to DeJesus' work ethic and emulate it.
"He's the ultimate professional who leads by example, and hopefully people do watch and ask him a lot of questions, because he does a lot of things well," Sveum said.
"I want to be the guy they see working hard every day, putting the time in, on and off the field, and who gives 100 percent on the field," DeJesus said. "That's ultimately all I care about is being the guy you can rely on every day."
There are plenty of young players on the current Cubs roster who should be paying attention. Twelve of the 29 players now on the Cubs active roster either opened the season at Triple-A Iowa or on another team's roster, including reliever Michael Bowden, who had his best outing. The right-hander struck out three over 2 1/3 innings in relief.
The Cubs now are 11-3 against the NL West at Wrigley Field after going 0-13 on the road against the Giants, Padres, Dodgers and D-backs.
While the Giants added Nady, who played for the Cubs in 2010, Chicago had reinforcements with the arrival of outfielders Dave Sappelt, Tony Campana and infielder Adrian Cardenas. Their seasons with Iowa ended early, as weekend games in New Orleans were canceled due to the hurricane.
"I said we can't go to a place in a 'state of emergency' to play a baseball game," Sappelt said.