The move will help the Cubs free up some salary for free agent Milton Bradley, who the team expects to sign this week after he undergoes a physical.
Marquis, who was 11-9 with a 4.53 ERA, is coming off his fifth consecutive double-digit win season. The right-hander was to be paid $9.875 million this year, the final year of the three-year contract he signed with the Cubs in December 2006. The Cubs are expected to pay $1 million of Marquis' '09 salary; Vizcaino is to make $4 million this year.
Vizcaino was 1-2 with a 5.28 ERA in 43 games last season with the Rockies, striking out 49 batters over 46 innings. The right-hander has a career 4.34 ERA over 10 seasons, including one year with the White Sox (6-5, 3.73 ERA in 2005).
Moving Marquis does not mean the Cubs will resume talks with the Padres regarding Jake Peavy but more likely that Sean Marshall will be looked at for the fifth spot in the rotation.
Carrie Muskat is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.