The Mariners entered Wednesday's rubber match with the Orioles having lost or tied seven consecutive series.
Since being recalled from Tacoma, reliever Oliver Perez has a 1.04 ERA in six games. The veteran made his first Major League appearance this season since 2010.
Reliever Charlie Furbush allowed a ninth-inning home run on Tuesday to snap his scoreless streak at 22 2/3 innings. It was the third-longest streak by a Mariners reliever. Closer Tom Wilhelmsen is tied for fifth on the list with an active scoreless streak of 19 2/3 innings.