The Nationals won three of four games against the Reds at Nationals Park last month in the opening home series of the season. Washington is seeking to secure just its third season-series win against Cincinnati since moving to D.C. in 2005.
First baseman Adam LaRoche entered Friday fifth in the National League with a 1.003 OPS. His on-base percentage of .421 and slugging percentage of .582 were both in the top eight of the NL.
The Nationals have allowed just 15 home runs this season, the lowest total in baseball. That will be tested this weekend at Great American Ball Park, dubbed by some locals as Great American "Small" Park.