The gates will open at 10 a.m. for the first game of the doubleheader, while the 6:10 p.m. game will be played at its originally scheduled time, with gates opening at 5 p.m.
It marks the first rainout at Target Field this season after three games were postponed in 2011.
Right-hander Jason Marquis was slated to start for the Twins opposite Royals left-hander Bruce Chen on Saturday, but both pitchers will be pushed back to Sunday.
Marquis will be followed in the rotation by right-hander Nick Blackburn, left-hander Francisco Liriano and right-hander Liam Hendriks. Right-hander Carl Pavano will start Friday's game against the Mariners in Seattle after an off-day on Thursday.
Fans holding tickets to Saturday's postponed game have two options. They can keep their tickets for admission into the rescheduled game on June 30, or exchange their tickets for a comparable ticket to an upcoming non-premium game during the 2012 regular season.
Fans who wish to exchange their tickets must mail the tickets to the Target Field ticket office to receive a voucher. Fans are also encouraged to visit twinsbaseball.com for more information regarding the club's rainout policy.