Colon broke a 1-1 tie in the fifth with a solo shot to left field. Colon, the Royals' No. 4 prospect, smacked an 0-1 pitch from starter Charles Brewer (D-backs).
"I faced him in college," said Colon, a Cal State-Fullerton product, of Brewer, a UCLA standout. "I knew he liked to throw his fastballs in[side]. He got me out with fastball in my first at-bat. ... I was looking for something in. I connected with it."
The Rockies' Nolan Arenado put the Rafters back up in the bottom of the fifth, 3-2, with his third home run in as many days. The Rockies' No. 4 prospect sent a 3-2 pitch from Ryan Kelly (Rangers) over the fence in left-center field. Each of his five fall home runs have come over his past eight games.
The Saguaros retied the score in the eighth on Myers' solo shot. The outfield prospect hit a 1-1 offering from Josh Zeid (Astros).
Zeid "started me off with a slider," said Myers. "I really wanted to see his fastball so I could time it, and then the third pitch was the fastball."
Through 14 AFL games, Myers, Kansas City's top prospect, is batting .396 with nine extra-base hits and 12 RBIs.
"He has just been himself," said Colon, who spent the 2011 regular season with Myers in Arkansas. "He is just letting his talent take over, and he is taking over. The kid is so talented. He can do anything he wants on the field."
This after a subpar season at Northwest Arkansas, where Myers batted .254 over 99 games.
"I really struggled this year in Double-A," the 21-year-old said, "and the main thing is just being confident at the plate."
The Saguaros scored the go-ahead run in the ninth. Seratelli, one of seven Royals on the club, walked, advanced to second on a balk and to third on a groundout before scored on a passed ball.
Colon, the No. 4 overall Draftee in 2010, singled home Kevin Mattison (Marlins) with two outs in the frame for the club's fifth and final run. Like Myers, he went 2-for-5 at the plate.
"Really awesome," Myers said, "to see the Royals out there having success."
Brewer allowed two runs on seven hits and struck out six over five innings. His counterpart, the Saguaros' Shane Dyer (Rays), yielded two runs on five hits over 4 2/3 frames.