Gyorko came to the plate with two teammates aboard and two outs in the bottom of the ninth. He laced a single into center field, again plating Centeno. Two batters later, fellow Padres farmhand Jaff Decker struck out to end the game.
"It always makes it better if you can get a 'W'," Gyorko said of his second career five-hit game.
All five of Gyorko's knocks came on fastballs.
"I was aggressive," Gyorko said. "I was looking for fastball all day."
San Diego's second-round draftee in 2010 recorded his first career five-hit game playing for Class A Advanced Lake Elsinore this season. He went 5-for-6 with a homer, two doubles and four RBIs in a 24-4 rout of Lancaster on June 7.
The 23-year-old slugger enjoyed a banner 2011 season. Splitting his time between the roles of designated hitter and third baseman, he batted .333 with 25 long balls and 114 RBIs in 140 games between Lake Elsinore and Double-A San Antonio. Both the Storm and Missions won league championships this season.
Through eight AFL games, Gyorko's bat has stayed hot. Including a two-homer, five-RBI game last Friday, the West Virginia University product is hitting .459, which puts him among the league leaders.
Javelinas starter Cody Scarpetta (0-1) couldn't record an out in the game's opening frame. Milwaukee's No. 7 prospect allowed seven runs on four hits, including a grand slam by Roberto Perez (Indians) and a two-run homer by Brodie Greene (Reds). Perez had entered the game with 2-for-22 at the plate in six games.
"We could have easily folded it up and went through the motions," Gyorko said. "When you play in Arizona, you're never out of the game. [Scarpetta] battled out there."
No. 2 Blue Jays prospect Anthony Gose led the Desert Dogs with three hits and a pair of stolen bases.
Gennett, as well as Mets prospects Centeno and Wilfredo Tovar, recorded three-hit games for the Javelinas.
Decker, San Diego's No. 4 prospect, went 1-for-6 at the plate, lowering his AFL average to .366.
Peoria (7-8) and Phoenix (5-10) remained in second and third place respectively in the three-team West Division.