The 2018 Interleague slate features visits to Baltimore by the Philadelphia Phillies (May 15-16), Washington Nationals (May 28-30), New York Mets (August 14-15), and Miami Marlins (June 15-17). The Orioles' road schedule against National League opponents will include visits to the Mets (June 5-6), as well as a series in Washington to play the Nationals (June 19-21), Atlanta Braves (June 22-24), and Phillies (July 3-4) as part of Interleague Play.
Baltimore will host the rest of the AL once: Cleveland Indians (April 20-23), Detroit Tigers (April 27-29), Kansas City Royals (May 8-10), Seattle Mariners (June 25-28), Los Angeles Angels (June 29-July 1), Texas Rangers (July 13-15), Oakland Athletics (September 11-13), Chicago White Sox (September 14-16), and Houston Astros (September 27-30).
The Orioles home schedule will also consist of four games played on national holidays including Easter (April 1 vs. Minnesota), Mother's Day (May 13 vs. Tampa Bay), Memorial Day (May 28 vs. Washington), and Father's Day (June 17 vs. Miami).
The Orioles will play 15 home games in June, their busiest month at Oriole Park. Overall, the Birds will play 50 of their 98 games prior to the All-Star break (July 16-19) at home. The Orioles have just one 10-game homestand: April 20-29 (Cleveland, Tampa Bay, and Detroit); one nine-game homestand: September 11-19 (Oakland, Chicago-AL, and Toronto); and one eight-game homestand: May 8-16 (Kansas City, Tampa Bay, and Philadelphia).
The Orioles will play 15 of the final 28 games of the season on the road. Baltimore will also travel for a 10-game road trip: May 18-27 (at Boston, Chicago-AL, and Tampa Bay), and two nine-game road trips: July 31-August 9 (at New York-AL, Texas, and Tampa Bay) and August 31-September 9 (at Kansas City, Seattle, and Tampa Bay). The Orioles will complete the road portion of their regular season schedule with a six-game road trip to New York-AL and Boston (September 21-26). The Orioles will finish the regular season at home with a four-game homestand, September 27-30 (Houston).