The AL's victory pulled it into a tie all-time in the event, at 43-43-2. In fact, both sides now have scored exactly 361 runs in those games.
However, this was the fifth straight win for the AL, which is now 17-3-1 going back to 1997.
Here are some other facts and figures to know about Tuesday's game:
• This was the 13th All-Star Game to go into extra innings and first since 2008 at the previous Yankee Stadium, when the AL pulled out a 4-3 victory on Michael Young's walk-off sacrifice fly against Brad Lidge in the 15th inning.
• No team had won the All-Star Game with as few as two runs scored since a 2-0 AL victory in 1990 at Wrigley Field.
• Cano hit just the fourth extra-innings homer in All-Star Game history and the first in exactly 50 years. On July 11, 1967, Tony Perez smacked a solo shot off another future Hall of Famer, Catfish Hunter, in the top of the 15th. The NL closed it out in the bottom of the frame to win, 2-1. Coincidentally, Perez was at Marlins Park on Tuesday night and threw out one of the ceremonial first pitches before the game.
• Cano was the first AL player to homer in extra innings of an All-Star Game. Perez (1967), Stan Musial ('55) and Red Schoendienst ('50) all did so for the NL.
• Cano joins a list of six other second basemen to hit go-ahead home runs in the Midsummer Classic. That group includes Lou Whitaker (1986), Joe Morgan (1977), Jackie Robinson (1952), Schoendienst (1950), Bobby Doerr (1943) and Frankie Frisch (1934).
• On a night where MLB honored its Latin American Hall of Famers with a pregame first pitch ceremony, the Dominican-born Cano's extra-inning heroics earned him All-Star Game MVP honors. Cano was also the World Baseball Classic MVP for the Dominican Republic in 2013, making him the only player to win MVP in both the World Baseball Classic and Midsummer Classic.
• Cano is the third Mariners player to be named MVP of an All-Star Game, and he's in good company. That last Mariner to win All-Star Game MVP was Ichiro Suzuki in 2007, when he went 3-for-3 with an inside-the-park home run, and also led off the game with a single. The Mariners' first All-Star Game MVP was Ken Griffey Jr. in 1992. Just 22 years old at the time, Griffey went 3-for-3 with a home run off fellow Hall of Famer Greg Maddux.
• Cano has six career home runs in extra innings. His last one came on Sept. 26, 2016, a tiebreaking shot in the 11th inning against the Astros' Luke Gregerson. Cano's first career extra-inning home run was a walk-off on Aug. 28, 2009, when he was still with the Yankees.
• Davis, who gave up the go-ahead home in the 10th inning, had a streak of 64 1/3 regular season innings without a homer snapped in May. Before his previous home run allowed on Sept. 24, 2015, he went 125 2/3 innings without giving up a home run, dating back to Aug. 24, 2013.
• After Miguel Sano's bloop single gave the AL a 1-0 lead in the fifth, the NL evened things up in the sixth on a solo shot to right field by Yadier Molina. It was the first opposite-field homer of the year for Molina.
Yadier Molina does something in the ASG he hasn't done all regular season -- homer to the opposite field. pic.twitter.com/1cQeQv50Yu
• Molina's home run made him the oldest catcher to homer in the All-Star Game, at 34 years, 363 days old. The previous oldest catcher with an All-Star Game home run was Yogi Berra, who was 34 years, 83 days old when he went yard in the 1959 Midsummer Classic.
• That Berra home run was the first by a catcher in an All-Star Game. Molina's is now the 18th. The most recent had been one of his AL counterparts, Salvador Perez, in last year's game.
• Molina became the first Cardinals player since Reggie Smith in 1974 to homer in the All-Star Game. Molina is the seventh Redbird to do so overall, joining Smith, Ken Boyer (twice), Musial (six times), Schoendienst, Frisch (twice) and Joe Medwick.
• Avisail Garcia of the White Sox had the hardest exit velocity of the night according to Statcast™ -- by more than 6 mph -- with a 113.1-mph line drive to left field in the seventh inning. Unfortunately for Garcia, it was caught by Michael Conforto, making it Garcia's hardest-hit out of the season.
• The most difficult catch of the All-Star Game, by Statcast™'s catch probability, was Bryce Harper's diving grab to rob Perez of a hit in the second inning. Harper's play had just a 60 percent catch probability, making it a three-star play by Statcast™'s ranking system. Harper was 3-for-6 on three-star catch opportunities this season entering the All-Star Game.
• Mookie Betts also made a fine play in center field for the AL, throwing out Nolan Arenado in the fourth inning when Arenado tried to tag up from first to second on Ryan Zimmerman's deep fly ball. Betts' arm strength on the 221-foot throw was 93.1 mph, per Statcast™, his second-hardest assist of 2017.
• Carlos Martinez of the Cardinals threw the three fastest pitches of the night, according to Statcast™, and seven of the eight that reached 100 mph (Craig Kimbrel had the other). Martinez topped out at 101 mph.
• Over his two innings of work, Martinez struck out four batters, joining Zack Greinke (2015) as the only pitchers to rack up that many K's in an All-Star Game since 2000. The only other Cardinals pitcher to accomplish that feat was Hall of Famer Dizzy Dean, who did it over three innings in 1934.
• The entire game was full of flamethrowers. The average four-seamer velocity in this year's All-Star Game was 96.5 mph, according to Statcast™. That's well higher than the average from the 2016 All-Star Game, 94.8 mph, and the 2015 All-Star Game, 95.3 mph.
• AL starter Chris Sale was one of the many pitchers throwing in the upper 90s, en route to two scoreless innings to begin the game. Sale topped out at 99.8 mph, according to Statcast™, during his first-inning at-bat against Harper. Sale hasn't thrown a pitch that hard in a regular-season game since 2015, when he also hit 99.8 mph once -- his 2017 max is 98.8 mph -- and he hasn't thrown a harder pitch since his rookie season in 2010.
• NL starting pitcher Max Scherzer struck out a pair in his only inning of work, whiffing T-Mobile Home Run Derby champion Aaron Judge and then George Springer to end the frame. Scherzer became the first pitcher in Nationals club history to pick up multiple K's in a Midsummer Classic. The last pitcher to do so in franchise history was Ugueth Urbina of the 1998 Expos.
• The AL's Jose Ramirez and Yonder Alonso both finished Tuesday's game with two hits and a stolen base. That's now been done 30 times in All-Star history. The last time a player had at least two hits and a steal was David Wright in 2010, and the last AL player was J.D. Drew in 2008. The only other Indians player to do so is Kenny Lofton (1996), and the only other A's player is Rickey Henderson (1982).
• Arenado, the NL starter at third base, singled in both of his at-bats for the first two All-Star hits of his career. That made him the first Rockies player to notch multiple hits in a single All-Star Game.
• In the top of the ninth inning, Dodgers closer Kenley Jansen worked around a leadoff single, stolen base and balk to keep the game tied for the NL. That was thanks to his typical dominant stuff -- he struck out the three other hitters he faced. It was the 13th time in All-Star Game history that a pitcher recorded three strikeouts in one inning of work, the most recent being Jacob deGrom and Aroldis Chapman in 2015. The only other Dodgers pitcher to do so was Jerry Reuss in 1980, while the last Los Angeles hurler to strike out three in an All-Star outing of any length was Greinke in his 2015 start.
• Miller worked around a two-out walk to nail down the save, becoming the fifth Indians pitcher to get one in an All-Star Game. Doug Jones was the last, in 1989, part of a group that also includes Hall of Famer Bob Feller ('39).
• NL starting shortstop Zack Cozart ripped a single off Dellin Betances in the third inning. The 106.8-mph exit velocity was the second hardest on any batted ball in the game and the second hardest on any batted ball by Cozart this season. At 97.9 mph, the pitch is tied for the second hardest Cozart has turned into a base hit in 2017.
Andrew Simon is a research analyst for MLB.com. David Adler is a reporter for MLB.com based in New York. Follow him on Twitter at @_dadler. This story was not subject to the approval of Major League Baseball or its clubs.