Edmonds stayed in the game -- a game eventually won by the Padres, 10-3 -- for one more inning before being replaced in center field by Callix Crabbe.
The Padres won't know exactly how long the injury will sideline the 37-year-old until at least Friday or possibly longer, according to manager Bud Black.
"We don't know how significant it is ... we'll wait a day or two," Black said, noting that Edmonds won't likely return to game action for at least two days.
Edmonds, who has one hit in six at-bats this spring, had remarked several times during camp how strong his legs felt, the result of a rigorous offseason workout program that was administered by a Los Angeles-based trainer who is a SWAT team member by day.
No hard feelings: It had been over five months since Jake Peavy last faced the Colorado Rockies, more than sufficient time for the Padres pitcher to stew over the events of that Wild Card playoff loss in extra innings that ended San Diego's season.
But if you think that the National League Cy Young Award winner carried any chip on his shoulder on Thursday or that he might have been motivated by revenge, well, think again.
"Zero emotion out there today," Peavy said, smiling.
Instead, Peavy had all his focus turned on one thing: throwing strikes and doing so more consistently than he did in his first Cactus League outing five days earlier when he struggled to locate his fastball down and away.
Peavy threw 50 pitches over three innings and allowed two runs on four hits with four strikeouts. Not only did he command his fastball, but Peavy mixed in his nasty slider, a few curveballs for fun and continued to work on his changeup.
"I threw it a lot," Peavy said of the changeup. "It can be an out pitch. I got some swings and misses today. It just depends on how it feels. I can throw a few in the 'pen. If I don't have it, I'm not going to work on it [in a game]."
On the mend: Relievers Justin Hampson and Kevin Cameron are itching to get back on the mound, though both are certainly being smart in not rushing their respective returns from minor injuries.
Hampson (sore left shoulder) and Cameron (strained left hamstring) haven't pitched in a week during drills, though both will likely make their Cactus League debuts on Friday.
For Cameron, who made the team last spring after being selected in the Rule 5 Draft, his hamstring feels much better than it did when he first injured it in a throwing drill. But he is cautious about rushing his return.
"It feels fully healthy now; just a matter of making sure I can cover the bases and come in on bunt plays," Cameron said. "It's something where we want to make sure it's healthy, because you don't want to tweak it again and have it set back even further."
Cameron said that while missing time -- and opportunities to throw -- is never good, this might be the only time where it's not working too badly against him.
"I have lost some time, but if you're going to lose time, early on is the time to do it," he said.
Camp cuts: The Padres announced on Thursday that they have reassigned five players to their Minor League camp.
The five players are pitchers Josh Geer, Edwin Moreno, Mike Megrew, Cesar Ramos and infielder Kyle Blanks.
The Padres now have 59 players in big league camp.
Friar notes: The Padres could be as close to full health as they've been all spring on Friday when pitchers Carlos Guevara and Cameron -- who both have missed time with hamstring injuries -- and Hampson take the mound against the Diamondbacks. Guevara has missed the most time, as he suffered a strained hamstring the first week of camp. Despite missing so much time, Black has said it won't affect his chances of making the team. ... Pitcher Arturo Lopez, a non-roster invitee, has left the team with permission to pitch for the Mexican national team.
Up next: Chris Young might be short on sleep but he'll make his second start of the spring on Friday when the Padres face Arizona at 12:05 p.m. PT at the Peoria Sports Complex. Young's daughter, Catherine Elizabeth, was born on Tuesday morning. Both Young's wife (Liz) and daughter are doing fine and were released from the hospital on Thursday.
Corey Brock is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.