But, for the second straight night, San Diego's bullpen did a stellar job of damage control, holding the D-backs to a run on three hits over the final six innings.
"It's tough," Padres manager Andy Green said of the extra usage of the bullpen. "We're carrying nine guys down there right now, and it's sad to say that it's tough on the bullpen with the amount of guys there are. And nobody's trying to go out there and have a bad outing.
"We probably left Perdomo out there longer than we should have, based on the state of the bullpen at this point in time."
Jose Valdez got the ball rolling for the bullpen in his Padres debut, taking over for Perdomo with runners on first and third and no outs in the fourth. After a walk loaded the bases, he was able to get Chris Herrmann to strike out and Rey Fuentes to line out to end the inning unscathed.
"[He had a] good slider, live fastball, that you can tell was jumping on guys," Green said. "He had a really good release, and he has the kind of stuff that, if he's in the strike zone and is able to keep his slider away, he has a chance to be good."
Valdez, who was called up from Triple-A El Paso on Saturday for Weaver, who was placed on the 10-day disabled list, fired a career-high three scoreless innings while giving up two hits and striking out three.
"Once I saw things weren't going well with Perdomo, I was making sure to get ready early, watching what he was doing, so I was able to come in and get those three innings," Valdez said.
The Padres have used seven relievers over the last two nights (not including shortstop Luis Sardinas who pitched the ninth inning Friday) and they've held Arizona to four runs through 15 1/3 innings.
"It's not fun when you're losing by that many runs, but it's a job to be done," said Craig Stammen, who pitched 3 1/3 innings on Friday. "It's what we get paid for -- to do the job you're asked of."
Jose Torres picked up right where Valdez left off, throwing two perfect innings before Brandon Maurer came in for the ninth. Maurer allowed the bullpen's only run of the game after Jake Lamb walked to open the inning and came around to score on a wild pitch.
Ryan Posner is a contributor to MLB.com based in San Diego. This story was not subject to the approval of Major League Baseball or its clubs.