In a separate incident, Royals pitcher Yordano Ventura died in a car crash in the Dominican as well. He was 25.
"Today is a very sad day for our entire game and particularly for the many loyal fans in the Dominican Republic, the home of both Yordano Ventura and Andy Marte," said Commissioner Rob Manfred.
"Yordano was a key figure in the Royals' recent success. His electric talent on the mound helped lead the Royals to two American League pennants and the 2015 World Championship. Andy was a respected member of six organizations who played seven Major League seasons, including for the Cleveland Indians from 2006-10. On behalf of Major League Baseball, I extend my deepest condolences to the families, teammates, friends and fans of both players."
Marte signed with the Braves in 2000 as an international free agent and was ranked No. 9 on MLB.com's 2005 Top 50 Prospects list.
After breaking into the Majors in 2005, he was traded to the Indians in '06 and spent five seasons with the club. His best year came in '09, when he hit .232 with six home runs and 25 RBIs in 47 games.
Marte played in just six games for the D-backs in 2014, before signing with the KT Wiz in South Korea. Over the last two seasons, he hit .312 and belted over 20 home runs both campaigns.
Wow! Sad to hear former teammate of mine Andy Marte passed away. Rest In Peace my friend! My thoughts and prayers are with your family.