Kipnis went 0-for-5 in Cleveland's 6-0 series-opening win.
• Game 2: Wednesday, 7 p.m. ET game time on FOX (6 p.m. ET pregame show on FS1)
"He ran last night," Francona said Tuesday. "I actually thought he ran better than I expected, and that's a situation where there's no people [in the stands]. I'm guessing that by the time 8 o'clock comes around, he'll be fine. He might be a half-step [slower than usual], but he'll be OK."
In the hours leading up to the start of the World Series, MLB Network's Heidi Watney tweeted a pair of photos of Kipnis' ankle, which looked extremely swollen in one picture and appeared badly bruised in the other. Kipnis said before Tuesday night's game that one photo was from last Wednesday after Cleveland clinched in Toronto, and the other was from a few days ago.
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Kipnis sustained a low ankle sprain after the Indians punched their ticket to the World Series with a win over the Blue Jays in Game 5 of the American League Championship Series. After the game's final out, Kipnis sprinted over to shortstop Francisco Lindor and jumped to embrace his teammate. As Kipnis landed, he rolled his left ankle.
During Sunday's workout at Progressive Field, Kipnis worked through a variety of fielding exercises with trainers closely monitoring his movements. The second baseman then took batting practice during a simulated game thrown by right-hander Danny Salazar. On Monday, Cleveland had Kipnis go through some baserunning drills, and he got through the workout fine.
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"I should be good," Kipnis said during Monday's media availability. "We're feeling good. We're progressing the way we had hoped. Right now, we're just getting out the swelling, getting range of motion back. If we can get it to where I can move around, the doctors have got stuff that can take pain away. I'll be all right."
Jordan Bastian has covered the Indians for MLB.com since 2011, and previously covered the Blue Jays from 2006-10. Read his blog, Major League Bastian, follow him on Twitter @MLBastian and listen to his podcast. This story was not subject to the approval of Major League Baseball or its clubs.