The players listed within this article are in position to provide difference-making stats for DraftKings participants on Wednesday.
Odubel Herrera: Having posted a lifetime .815 OPS against right-handers that exceeds his .662 mark vs. lefties, the outfielder has the skills to reach base often against righty Mike Foltynewicz (career 4.99 ERA, 1.46 WHIP) and a Braves bullpen that ranks 20th with a 4.03 ERA. Herrera could also swipe a base against catcher Tyler Flowers, who has thrown out three of 60 would-be basestealers this season.
Trea Turner: During his impressive rookie season, Turner has produced a lofty .978 OPS against right-handers in comparison to a .696 mark vs. lefties. The outfielder could post a game-changing DraftKings total when he faces righty Shelby Miller (6.47 ERA, 1.70 WHIP in 2016) and a D-backs squad that ranks 29th in the Majors with a .666 defensive efficiency ratio.
Paul Goldschmidt: With a lifetime .336/.440/.601 slash line against left-handers, the first baseman has proven to wield a potent bat in those matchups. Goldschmidt could have an outstanding game when he faces Nationals southpaw Gio Gonzalez, who has a 4.51 ERA and a 1.31 WHIP this season.
Corey Seager: Hitting .313 with 26 homers and 103 runs across 668 plate appearances, the shortstop is putting the final touches on a memorable rookie season. Seager could continue to thrive when he brings his impressive lifetime .338/.398/.568 slash line against right-handers into a matchup with rookie righty Luis Perdomo (5.59 ERA, 1.59 WHIP) and a Padres relief corps that ranks 22nd in baseball with a 4.14 ERA.
Adrian Gonzalez: From the heart of the lineup, the first baseman could drive in multiple runs when he brings his lifetime 140 wRC+ against right-handers (108 vs. lefties) into a matchup with the right-handed Perdomo and an unreliable Padres bullpen.
Corey Dickerson: With 23 homers across 485 at-bats this season and a solid lifetime .889 OPS against right-handers (.655 vs. lefties), the outfielder is a strong candidate to rip a roundtripper during a matchup against fly-ball-prone righty Miguel Gonzalez (career 1.2 HR/9 rate) at homer-happy U.S. Cellular Field.
Brad Miller: Eligible at first base and shortstop, Miller can enter DraftKings lineups in multiple ways when he brings his lifetime .207 ISO against right-handers (.095 vs. lefties) into a matchup with the homer-prone Gonzalez (career 4.53 FIP) at Chicago's hitter-friendly venue. With 30 homers across 533 at-bats, Miller has made major power improvements this season.
Curtis Granderson: The owner of a lifetime .367 wOBA against right-handers in comparison to a .307 mark vs. lefties, Granderson has the skills to excel against Marlins righty Jose Urena (career 5.64 ERA, 1.48 WHIP). In his career, Urena has allowed left-handed hitters such as Granderson to post an .841 OPS (.747 OPS allowed to righty batters).
Mitch Moreland: With a lifetime .782 OPS against right-handers that exceeds his .671 mark vs. lefties, the first baseman will be in prime position to go deep when he bats at his offense-inducing home park against Brewers righty Chase Anderson (4.36 ERA, 1.35WHIP in 2016).
Nomar Mazara: The rookie outfielder will be in excellent position to improve on his solid .282/.337/.472 slash line against right-handers when he tangles with the right-handed Anderson (career 4.24 ERA, 1.34 WHIP) and a Brewers bullpen that lacks reliable options after trading Will Smith and Jeremy Jeffress in late July.
Brian Dozier: With 42 homers across 598 at-bats, the second baseman has been one of the most powerful players in baseball this season. Dozier could continue his memorable campaign when he takes his lifetime .860 OPS against left-handers (.732 vs. righties) into a matchup with Royals lefty Jason Vargas (career 4.19 ERA, 1.31 WHIP), who is making his third start since returning from Tommy John surgery.
Denard Span: The outfielder has long fared best vs. right-handers, against whom he owns a lifetime 109 wRC+ (94 vs. lefties). Span could reach base often and score multiple runs when he tangles with righty Tyler Chatwood (career 4.26 ERA, 1.51 WHIP) and a Rockies relief corps that ranks last in baseball with a 5.02 ERA.
Stephen Vogt: With a lifetime 110 wRC+ against right-handers that exceeds his 71 mark vs. lefties, the catcher could provide production from his premium position when he faces righty Alex Meyer (career 7.13 ERA, 1.79 WHIP). Vogt could also thrive late in the game against an Angels bullpen that will work without injured anchors Huston Street and Cam Bedrosian.
Mike Trout: With a lifetime .311/.405/.569 slash line against right-handers, the outfielder has proven to be among the best during those matchups. Trout could post a game-changing DraftKings total when he faces A's righty Sonny Gray, who owns a 5.74 ERA this season and hasn't pitched since Aug. 6 due to injury.
Francisco Liriano: After struggling during his time with the Pirates this season, Liriano has posted a 3.35 ERA across 43 innings with the Blue Jays. The left-hander could continue to limit the opposition when he faces an Orioles lineup that ranks 26th in baseball with a .691 OPS against lefties.
Jake Arrieta: Having posted a 2.44 ERA and a 0.97 WHIP since joining the Cubs during the 2013 season, the right-handers ranks among the most effective starters in baseball. Arrieta could post a substantial DraftKings total when he faces a Pirates lineup that ranks 25th in the Majors with a .145 ISO against righties.
Ervin Santana: With a 2.59 ERA across 13 starts, the right-hander has been one of the most effective pitchers in baseball during the second half of the season. Santana could complete his dominant finish when he takes on a Royals lineup that ranks last in baseball with a .131 ISO against righties.
All statistics are accurate through the completion of Monday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.