Carlos Gonzalez: In his career, the outfielder has fared best when facing right-handers (.926 OPS) and when batting at his hitter-friendly home park (1.016 OPS). CarGo could post a substantial DraftKings total when he hits at home against righty Edwin Jackson (5.32 ERA, 1.54 WHIP in 2016) and a Padres relief corps that ranks 24th in baseball with a 4.25 ERA.
Charlie Blackmon: From his perch atop the lineup, the outfielder could reach base often and score multiple runs when he brings his lifetime 108 wRC+ against right-handers (93 vs. lefties) into a matchup at his offense-inducing home park against the right-handed Jackson (career 4.61 ERA, 1.45 WHIP) and a Padres squad that ranks 22nd in baseball with a .684 defensive efficiency ratio.
DJ LeMahieu: With a .412/.491/.561 slash line since Aug. 1, the second baseman will bring a hot bat and balanced lifetime splits into a home matchup against Jackson (5.32 ERA, 1.54 WHIP in 2016) and an unreliable Padres bullpen.
Corey Seager: Hitting .316 with 25 homers and 96 runs across 621 plate appearances, the shortstop is wrapping up an outstanding rookie season. Seager could continue to excel when he brings his impressive lifetime .343/.401/.572 slash line against right-handers into a matchup at homer-happy Chase Field with righty Shelby Miller (7.12 ERA, 1.76 WHIP in 2016) and a D-backs squad that ranks last in the Majors with a .662 defensive efficiency ratio.
Adrian Gonzalez: From the heart of the lineup, the first baseman could drive in multiple runs when he vacates his pitcher-friendly home park and bats at Arizona's offense-inducing venue against the right-handed Miller. Gonzalez could also thrive late in the game against a D-backs relief corps that ranks 29th in baseball with a 5.13 ERA.
Mitch Moreland: The first baseman has long fared best vs. right-handers, against whom he has produced a lifetime 108 wRC+ (77 vs. lefties). Moreland could put a ball into the outfield seats or drive in multiple runs when he bats at his hitter-friendly home park against A's rookie righty Raul Alcantara, who has posted a 7.27 ERA and a 1.62 WHIP across his initial two starts.
Nomar Mazara: The rookie outfielder will be in prime position to improve on his solid .278/.336/.465 slash line against right-handers when he bats at his offense-inducing home park against the inexperienced righty Alcantara.
Edwin Encarnacion: With 36 homers and 116 RBIs across 541 at-bats, the first baseman has produced elite power totals this season. From the heart of the lineup, Encarnacion could drive in multiple runs when he faces Angels righty Ricky Nolasco (4.94 ERA, 1.28 WHIP in 2016).
Devon Travis: Hitting leadoff, the second baseman may maximize his opportunities to reach base and score runs when he brings his lifetime 125 wRC+ against right-handers (104 vs. lefties) into a matchup with the right-handed Nolasco (career 4.58 ERA, 1.32 WHIP). Travis could also excel late in the game against an Angels bullpen that is working without injured anchors Huston Street and Cam Bedrosian.
Chris Davis: The left-handed-hitting first baseman will be primed to rip his 38th round-tripper of the season when he bats at his hitter-friendly home park against righty Matt Andriese (4.46 ERA in 2016) and a Rays relief corps that ranks 23rd in the Majors with a 4.16 ERA. Also working in Davis' favor: Camden Yards has proven to be especially power-inducing for southpaw sluggers.
Jonathan Schoop: With 24 homers across 555 at-bats, the second baseman has been one of the most powerful players at his premium position this season. Schoop could go deep or drive in multiple runs when he brings his lifetime .209 ISO against right-handers (.107 vs. lefties) into a matchup at his offense-inducing home park against the right-handed Andriese (career 4.33 ERA) and an unreliable Rays bullpen.
Ryan Schimpf: With 19 homers across 236 at-bats, the second baseman is quickly becoming one of the most powerful players at his premium position. Schimpf could put another ball into the outfield seats when he bats at homer-happy Coors Field against righty Jon Gray (career 4.87 ERA, 1.35 WHIP) and a Rockies relief corps that ranks last in the Majors with a 5.13 ERA.
Jean Segura: Hitting .315 with 90 runs and 30 steals across 626 plate appearances, the second baseman has been one of the most productive players at his premium position this season. Segura could reach base often and score multiple runs when he bats at his hitter-friendly home park against Dodgers rookie righty Brock Stewart (6.55 ERA, 1.73 WHIP).
Jake Lamb: In his breakout 2016 season, the third baseman has registered a .931 OPS against right-handers that exceeds his .648 mark vs. lefties. Lamb could add to his impressive 2016 totals of 28 homers and 88 RBIs across 472 at-bats when he bats at his offense-inducing home venue against the rookie righty Stewart.
Jose Urena: DraftKings participants who look past the right-hander's lifetime 5.05 ERA will notice that he has posted a 2.30 ERA and a 0.93 WHIP across his past five starts. Urena could continue his successful stretch run when he faces a Phillies lineup that ranks 29th in the Majors with a .687 OPS against righties.
Gio Gonzalez: With a 4.27 ERA this season, the left-hander could have a reasonable price tag in DraftKings contests when he faces a Braves lineup that ranks last in baseball in OPS vs. lefties (.103) and total home runs (108). Gonzalez's chances of earning a win could be enhanced by a Washington bullpen that leads the Majors with a 3.22 ERA.
David Price: With a 2.16 ERA and a 0.82 WHIP across his past seven starts, the left-hander has found his form after an inconsistent beginning to the season. Price could continue his strong finish when he faces a Yankees lineup that ranks 25th in baseball with a .695 OPS against southpaws.