The players listed below are in position to provide difference-making stats for DraftKings participants on Monday.
Dustin Pedroia: In his productive career, the second baseman has registered an impressive .306/.391/.458 slash line against left-handers. Pedroia could thrive from his perch atop a Red Sox lineup that leads the Majors with 779 runs scored when he faces Orioles southpaw Wade Miley (career 4.18 ERA, 1.35 WHIP).
Mookie Betts: Hitting .315 with 30 homers, 23 steals and 107 runs across 643 plate appearances, the outfielder has made a major impact in many 2016 DraftKings contests. From the heart of a productive Boston lineup, Betts could contribute in multiple ways against Miley (5.49 ERA, 1.42 WHIP in 2016).
Xander Bogaerts: Hitting .298 with 18 homers, 81 RBIs and 100 runs scored across 630 plate appearances, the shortstop has been one of the most productive players at his premium position this season. Bogaerts could continue to excel when he brings his lifetime .367 wOBA against left-handers (.312 vs. righties) into a matchup with Miley.
Joey Votto: With a .427/.518/.669 slash line in the second half, the first baseman will be in fine form when he brings his impressive lifetime .317/.436/.549 slash line against right-handers into a matchup with Brewers righty Wily Peralta (5.47 ERA, 1.59 WHIP in 2016). In his career, Peralta has allowed left-handed hitters such as Votto to post an .825 OPS (.710 OPS allowed to righty batters).
Jose Altuve: The second baseman could improve on his impressive 2016 statistics (.339 average, 22 homers, 27 steals across 632 plate appearances) when he brings his stellar lifetime .350/.400/.504 slash line against left-handers into a matchup with Rangers southpaw Martin Perez (career 4.23 ERA, 1.41 WHIP).
George Springer: Hitting leadoff, the outfielder may maximize his opportunities to reach base or display his power when he brings his lifetime .392 wOBA against left-handers (.341 vs. righties) into a matchup with Perez (4.25 ERA, 1.43 WHIP in 2016) and a Rangers relief corps that ranks 27th in the Majors with a 4.76 ERA.
Corey Seager: Hitting .319 with 25 homers and 95 runs across 600 plate appearances, the shortstop is in the final weeks of an impressive rookie season. Seager could improve on his excellent lifetime .343/.403/.580 slash line against right-handers when he vacates his pitcher-friendly home park and bats at homer-happy Yankee Stadium against righty Bryan Mitchell (career 4.73 ERA, 1.58 WHIP).
Adrian Gonzalez: Hitting .292 with 78 RBIs across 504 at-bats, the veteran first baseman continues to be one of the most reliable hitters in baseball. Gonzalez could drive in multiple runs when he brings his lifetime .379 wOBA against right-handers (.332 vs. lefties) into a matchup with Mitchell at Yankee Stadium, which has proven to be especially power-inducing for left-handed hitters such as Gonzalez.
Carlos Gonzalez: The outfielder will be ready to post a difference-making DraftKings total when he brings his lifetime .926 OPS against right-handers (.754 vs. lefties) into a matchup at hitter-friendly Chase Field with righty Shelby Miller (6.89 ERA, 1.74 WHIP in 2016) and a D-backs relief corps that ranks last in baseball with a 5.18 ERA.
Charlie Blackmon: From his perch atop the lineup, the outfielder could reach base often or score multiple runs when he takes his lifetime .820 OPS against right-handers (.753 vs. lefties) into a matchup with Miller and a D-backs squad that ranks 29th in the Majors with a .664 defensive efficiency ratio.
Robinson Cano: Hitting .301 with 32 homers and 86 RBIs across 571 at-bats, the second baseman continues to be one of the top producers at his premium position. Cano could have an excellent game when he brings his lofty lifetime .891 OPS against right-handers (.778 vs. lefties) into a matchup with Angels righty Ricky Nolasco (career 4.58 ERA, 1.32 WHIP).
Kyle Seager: The third baseman could add to his impressive 2016 totals of 28 homers and 92 RBIs across 520 at-bats when he takes his lifetime .355 wOBA against right-handers (.314 vs. lefties) into a matchup with the right-handed Nolasco (4.90 ERA, 1.28 WHIP in 2016). Seager could also excel late in the game against an Angels bullpen that will operate without injured anchors Huston Street and Cam Bedrosian.
Mike Trout: The outfielder has proven to be one of the best in baseball against left-handers by posting a lifetime .291/.402/.521 slash line in those matchups. Trout could record a substantial DraftKings total when he faces Mariners rookie southpaw Ariel Miranda (4.79 ERA, 1.37 WHIP).
Albert Pujols: Hitting behind Trout, the first baseman -- who ranks third in baseball with 110 RBIs -- could drive in multiple runs when he brings his impressive lifetime .314/.402/.599 slash line against left-handers into a matchup with Miranda (35 2/3 innings).
Gerrit Cole: With a 2.93 ERA since the outset of 2015, the right-hander has the skills to have a major impact in DraftKings contests when he returns from the disabled list to face a Phillies lineup that ranks 29th in the Majors with a .686 OPS against righties.
Andrew Cashner: With a 4.77 ERA and a 1.46 WHIP this season, the right-hander could have a reasonable price tag in DraftKings contests when he works at pitcher-friendly Turner Field against a Braves lineup that ranks 28th in the Majors in ISO vs. righties (.135) and last in total home runs (103).
All statistics are accurate through the completion of Saturday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.