The players listed below are in position to provide difference-making stats for DraftKings participants on Tuesday.
Josh Donaldson: Since joining the Blue Jays at the outset of 2015, the third baseman has registered a 1.009 OPS against left-handers (.929 vs. righties) and a 1.013 OPS at his hitter-friendly home park (.876 on the road). Donaldson could go deep or score multiple runs when he hits at home against Angels lefty Tyler Skaggs (career 4.78 ERA, 1.32 WHIP).
Troy Tulowitzki: The shortstop will be primed to rip his 22nd round-tripper of the season or drive in multiple runs when he brings his lifetime 142 wRC+ against left-handers (115 vs. righties) into a matchup at his offense-inducing home park against the left-handed Skaggs. Since returning from Tommy John surgery, Skaggs has posted a 5.19 ERA and a 1.58 WHIP across five starts.
Melvin Upton Jr.: In his bounceback 2016 season, the outfielder has produced a .947 OPS against left-handers in comparison to a .649 mark vs. righties. Upton could thrive in a matchup against the left-handed Skaggs and an Angels bullpen that will work without injured anchors Huston Street and Cam Bedrosian.
Mike Trout: With a lifetime .312/.403/.572 slash line against right-handers, the outfielder has proven to wield a potent bat during those matchups. Trout could post a notable DraftKings total when he vacates his pitcher-friendly home park and works at homer-happy Rogers Centre against righty R.A. Dickey (4.51 ERA, 1.6 HR/9 rate in 2016).
Kris Bryant: With 31 homers, 99 runs and a .392 on-base percentage across 541 plate appearances, the third baseman has been one of the most productive players in baseball this season. From the heart of a Cubs lineup that ranks third in baseball with 631 runs scored, Bryant could produce a game-changing DraftKings total at the expense of Christian Friedrich (4.69 ERA, 1.46 WHIP in 2016) and a Padres bullpen that ranks 25th in baseball with a 4.44 ERA.
Javier Baez: Eligible at second base and third base in DraftKings contests, Baez could have a terrific game when he brings his lifetime .349 wOBA against left-handers (.275 vs. righties) into a matchup with the left-handed Friedrich (career 5.41 ERA, 1.55 WHIP). He could also swipe a base against Derek Norris, who has allowed more steals than any other catcher in 2016.
Carlos Gonzalez: With a lifetime .258 ISO against right-handers that exceeds his .182 mark vs. lefties, the outfielder could have a great game when he bats at hitter-friendly Miller Park against righty Chase Anderson (4.97 ERA, 1.41 WHIP in 2016) and a Brewers bullpen that lacks reliable options after trading away Jeremy Jeffress and Will Smith in late July.
Chris Davis: With five homers across 17 at-bats since Aug. 17, the left-handed-hitting first baseman will bring a red-hot bat and a lifetime .868 OPS against right-handers (.746 vs. lefties) into a matchup at his hitter-friendly home park against Nationals rookie righty Reynoldo Lopez (4.37 ERA, 1.46 WHIP). Also working in Davis' favor: Camden Yards has proven to be especially power inducing for southpaw sluggers.
Stephen Piscotty: With a lifetime .313/.398/.559 slash line against left-handers, the outfielder is quickly becoming one of the best in baseball during those matchups. Piscotty could have a great game when he faces Mets lefty Jon Niese, who has posted a 5.30 ERA and a 1.57 WHIP this season.
Jedd Gyorko: Eligible at second base and third base, Gyorko could enter DraftKings lineups in multiple ways when he brings his lifetime .737 OPS against left-handers (.697 vs. righties) into a matchup with the left-handed Niese (career 4.05 ERA, 1.38 WHIP).
Jake Lamb: In his breakout 2016 season, the third baseman has produced 24 homers and 75 RBIs across 401 at-bats primarily on the strength of a .945 OPS against right-handers (.612 vs. lefties). Lamb could have a great game when he bats at his hitter-friendly home park against Braves rookie righty Rob Whalen (5.73 ERA).
Carlos Correa: This season, the shortstop has posted an .865 OPS against right-handers that exceeds his .742 mark vs. lefties. From the heart of the lineup, Correa could drive in multiple runs when he faces Pirates righty Ivan Nova (4.83 ERA, 1.35 WHIP in 2016).
Scooter Gennett: With lopsided lifetime splits that include a 108 wRC+ against right-handers in comparison to a 24 mark vs. lefties, Gennett will be primed to excel when he bats at his hitter-friendly home park against righty Jon Gray (career 4.89 ERA, 1.34 WHIP) and a Rockies squad that ranks 28th in baseball with a .672 defensive efficiency ratio.
Adam Eaton: From a premium lineup spot, the outfielder may maximize his opportunities to reach base and score runs when he takes his lifetime .784 OPS against right-handers (.709 vs. lefties) into a matchup at his hitter-friendly home park against Phillies rookie righty Jake Thompson (8.79 ERA, 1.60 WHIP)
Jake Arrieta: With a 2.39 ERA and a 0.97 WHIP since joining the Cubs during the 2013 season, the right-hander could post an outstanding DraftKings total when he works at pitcher-friendly Petco Park against a Padres lineup that ranks last in the Majors with a .679 OPS against righties. Also working in Arrieta's favor: Chicago leads the Majors by a wide margin with a .733 defensive efficiency ratio.
Madison Bumgarner: With a 2.25 ERA and a 1.02 WHIP this season, the left-hander continues to rank among the most reliable aces in baseball. Bumgarner could post a substantial DraftKings total when he works at pitcher-friendly Dodger Stadium against a Los Angeles lineup that ranks 29th in baseball with a .657 OPS against lefties.
Danny Salazar: With a 3.50 ERA and a 9.8 K/9 rate since the outset of 2015, the right-hander has the skills to compile six-plus effective innings and a handful of strikeouts when he works at pitcher-friendly Oakland Coliseum against an A's lineup that ranks 24th in the Majors with a .706 OPS against righties.
All statistics are accurate through the completion of Sunday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.