The players listed below are in position to provide difference-making stats for DraftKings participants on Monday.
Carlos Gonzalez: With a lifetime .258 ISO against right-handers that exceeds his .183 mark vs. lefties, the outfielder could have a great game when he bats at hitter-friendly Miller Park against righty Jimmy Nelson (4.31 ERA, 1.49 WHIP in 2016).
DJ LeMahieu: Hitting .341 with a .413 on-base percentage this season, the second baseman has the skills to reach base often when he brings his balanced lifetime splits into a matchup with Nelson and a Brewers bullpen that lacks reliable options after trading away Jeremy Jeffress and Will Smith in late July.
Addison Russell: The second-year shortstop will be in great position to improve on his lifetime 103 wRC+ against right-handers (69 vs. lefties) when he faces righty Edwin Jackson (career 4.60 ERA, 1.51 WHIP). Russell could also thrive late in the game against a Padres bullpen that ranks 26th in the Majors with a 4.46 ERA.
Anthony Rizzo: With 25 homers, 87 RBIs and a .395 on-base percentage across 522 plate appearances, the first baseman has been one of the most productive players in baseball this season. From the heart of a Cubs lineup that ranks third in baseball with 627 runs scored, Rizzo could produce a game-changing DraftKings total at the expense of Jackson (5.36 ERA, 1.51 WHIP in 2016) and an unreliable Padres bullpen.
Scooter Gennett: The second baseman owns lopsided lifetime splits, with a .778 OPS against right-handers in comparison to a .480 mark vs. lefties. Gennett could provide production at a premium position when he bats at his hitter-friendly home park against righty Chad Bettis (career 5.25 ERA, 1.53 WHIP) and a Rockies relief corps that ranks 28th in baseball with a 4.80 ERA.
Kirk Nieuwenhuis: With 11 homers and eight steals across 330 plate appearances, the outfielder has the skills to produce in multiple ways when he brings his lifetime 102 wRC+ against right-handers (37 vs. lefties) into a matchup with the right-handed Bettis (5.29 ERA, 1.49 WHIP in 2016) and a Rockies squad that ranks 28th in the Majors with a .671 defensive efficiency ratio.
Jake Lamb: In his breakout 2016 season, the third baseman has produced 24 homers and 75 RBIs across 397 at-bats primarily on the strength of a .956 OPS against right-handers (.612 vs. lefties). Lamb could have a great game when he bats at his hitter-friendly home park against Braves righty Mike Foltynewicz (career 5.09 ERA, 1.48 WHIP).
Michael Bourn: The outfielder could reach base often or score multiple runs when he brings his lifetime .703 OPS against right-handers (.637 vs. lefties) into a matchup with the right-handed Foltynewicz (4.45 ERA, 1.31 WHIP in 2016). In his career, Foltynewicz has allowed left-handed hitters such as Bourn to post a .922 OPS (.767 OPS allowed to righty batters).
Jason Kipnis: From the No. 2 spot in the lineup, the second baseman could reach base often or score multiple runs when he brings his lifetime 124 wRC+ against right-handers (91 vs. lefties) into a matchup with A's rookie righty Andrew Triggs (4.98 ERA, 1.38 WHIP).
Tyler Naquin: The rookie outfielder will be in prime position to improve on his impressive .322/.378/.616 slash line against right-handers when he faces the rookie righty Triggs and an A's squad that is tied for 20th in the Majors with a .683 defensive efficiency ratio.
Lonnie Chisenhall: The outfielder has long fared best vs. right-handers, against whom he has logged a lifetime .745 OPS (.667 vs. lefties). Chisenhall could serve as a cost-effective member of DraftKings squads when he faces the rookie righty Triggs.
Robinson Cano: In his productive career, the second baseman has produced an impressive .891 OPS against right-handers (.776 vs. lefties). From the No. 3 spot in the lineup, Cano could display his power when he faces Yankees righty Michael Pineda (4.89 ERA, 1.4 HR/9 rate in 2016).
Seth Smith: With a lifetime 122 wRC+ against right-handers (60 vs. lefties) the outfielder will be primed to produce when he faces the right-handed Pineda (1.33 WHIP in 2016). Smith could be part of a productive lineup, as the Mariners rank sixth in the Majors with a .768 OPS against righties.
Jameson Taillon: With a 3.00 ERA and a 1.09 WHIP, the right-hander has been one of the most effective rookie hurlers this season. Taillon could continue his strong debut campaign when he works at his pitcher-friendly home park against an Astros squad that ranks third in the Majors in strikeouts (1,125) and will have to work without the designated hitter position at a National League venue.
Zack Godley: With a 4.85 ERA and a 1.31 WHIP this season, the right-hander could be a reasonably priced second starter in DraftKings contests when he faces a Braves lineup that ranks 29th in the Majors in ISO vs. righties (.128) and last in total home runs (83).
Carlos Carrasco: Having posted a 3.22 ERA, a 1.05 WHIP and a 9.8 K/9 rate since the outset of 2014, the right-hander has the skills to post an outstanding DraftKings total when he works at pitcher-friendly Oakland Coliseum against an A's lineup that ranks 25th in the Majors with a .706 OPS against righties.
All statistics are accurate through the completion of Saturday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB. This story was not subject to the approval of Major League Baseball or its clubs.