The players listed below are in position to provide difference-making stats for DraftKings participants on Tuesday.
David Ortiz: The left-handed-hitting slugger will be primed to rip a round-tripper when he brings his impressive lifetime .308 ISO against right-handers (.211 vs. lefties) into a matchup at hitter-friendly Camden Yards against Orioles righty Yovani Gallardo (5.17 ERA, 1.60 WHIP in 2016). Also working in Ortiz's favor: Baltimore's venue has proved to be especially homer-happy for lefty sluggers.
Anthony Rizzo: From the heart of a talent-laden Cubs lineup, the first baseman could produce a substantial DraftKings total when he takes his lifetime .874 OPS against right-handers (.780 vs. lefties) into a matchup with righty Chase Anderson (4.93 ERA, 1.41 WHIP in 2016) and a Brewers bullpen that lacks reliable options after trading away Jeremy Jeffress and Will Smith in late July.
Addison Russell: The second-year shortstop owns notable lifetime splits, with a .760 OPS against right-handers compared with a .597 mark vs. lefties. As part of a Cubs lineup that ranks third in baseball with 589 runs scored, Russell could excel against the right-handed Anderson (career 4.40 ERA, 1.35 WHIP) and an unsettled Brewers bullpen.
Bryce Harper: Hitting .143 since the All-Star break, the reigning National League MVP could have a reduced price tag in DraftKings contests when he brings his impressive lifetime .937 OPS against right-handers (.773 vs. lefties) into a matchup at homer-happy Coors Field against righty Chad Bettis (career 5.24 ERA, 1.53 WHIP) and a Rockies relief corps that ranks 28th in the Majors with a 4.85 ERA.
Daniel Murphy: Hitting .348 with 22 homers and 86 RBIs across 411 at-bats, the second baseman has been one of the most productive players in baseball this season. Murphy could put a ball into the outfield seats or drive in multiple runs when he brings his lifetime .809 OPS against right-handers (.705 vs. lefties) into a matchup with the right-handed Bettis (5.27 ERA, 1.47 WHIP in 2016) at Colorado's offense-inducing venue.
Nomar Mazara: The rookie outfielder could improve on his solid .298/.356/.471 slash line against right-handers when he bats at his hitter-friendly home park against the inexperienced righty Triggs (37 2/3 innings) and an A's squad that ranks 23rd in the Majors with a .682 defensive efficiency ratio.
Mitch Moreland: As a big leaguer, the first baseman has posted a .797 OPS against right-handers that exceeds his .671 mark vs. lefties. On Tuesday, Moreland could homer or drive in multiple runs when he faces the rookie righty Triggs.
Stephen Vogt: The catcher has long fared best vs. right-handers, against whom he has produced a lifetime 111 wRC+ (75 vs. lefties). Vogt could provide production at a premium position when he vacates his pitcher-friendly home park and bats at offense-inducing Globe Life Park in Arlington against righty Lucas Harrell (career 4.78 ERA, 1.56 WHIP) and a Rangers relief corps that ranks 27th in the Majors with a 4.68 ERA.
Nolan Arenado: In his career, the third baseman has fared best vs. left-handers (.877 OPS) and at his hitter-friendly home park (.937 OPS). Arenado could have a great game when he hits at home against Nationals southpaw Gio Gonzalez (4.24 ERA, 1.32 WHIP in 2016).
Robinson Cano: Much of Cano's impressive career statistics can be traced to his lifetime .891 OPS against right-handers (.775 vs. lefties). From the No. 3 spot in the lineup, the second baseman could produce a substantial DraftKings total when he faces righty Jhoulys Chacin (5.84 ERA, 1.53 WHIP in 2016) and an Angels bullpen that will work without injured anchors Huston Street and Cam Bedrosian.
Seth Smith: With a lifetime 122 wRC+ against right-handers that exceeds his 60 mark vs. lefties, the outfielder will be in great position to thrive against the right-handed Chacin (career 4.02 ERA, 1.36 WHIP). In his career, Chacin has allowed left-handed hitters such as Smith to post a .776 OPS (.673 OPS allowed to righty batters).
Kyle Seager: With a lifetime .354 wOBA against right-handers that exceeds his .307 mark vs. lefties, the third baseman could drive in multiple runs when he tangles with the right-handed Chacin and an unsettled Angels bullpen.
Max Kepler: With 15 homers and 52 RBIs across 252 at-bats, the outfielder has been one of the most productive rookies in baseball this season. Kepler could continue his excellent campaign when he brings his lifetime .911 OPS against right-handers (.639 vs. lefties) into a matchup with Braves rookie righty Joel De La Cruz (4.09 ERA, 1.39 WHIP).
Ervin Santana: With a 2.05 ERA and a 0.95 WHIP across his past nine starts, the right-hander has been a positive contributor to many recent DraftKings squads. Santana could continue to limit the opposition when he faces a Braves lineup that ranks 29th in baseball in ISO vs. righties (.126) and last in total home runs (79).
Kenta Maeda: With a 3.31 ERA and a 1.09 WHIP, the rookie righty has enjoyed an impressive debut season. Maeda could compile six-plus effective innings when he tangles with a Phillies lineup that ranks 28th in the Majors with a .696 OPS against righties.
Corey Kluber: With a 3.02 ERA, a 1.06 WHIP and a 9.8 K/9 rate since the outset of 2014, the right-hander has the skills to spin a gem when he works at home against a White Sox lineup that ranks 24th in the Majors with a .707 OPS against righties.
All statistics are accurate through the completion of Sunday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.