The players listed below are in position to provide difference-making stats for DraftKings participants on Sunday.
Xander Bogaerts: Hitting .324 with 61 RBIs and 71 runs across 425 plate appearances, the shortstop has been one of the most productive players at his premium position this season. Hitting third in a Red Sox lineup that leads the Majors with 530 runs scored, Bogaerts could produce in multiple ways when he brings his lifetime .847 OPS against left-handers (.720 vs. righties) into a matchup against southpaw Tommy Milone (career 4.02 ERA, 1.31 WHIP) and a Twins bullpen that ranks 24th in baseball with a 4.47 ERA.
Dustin Pedroia: The second baseman has long fared best vs. left-handers, against whom he has posted a lifetime .844 OPS (.796 vs. righties). Pedroia could have a great game when he tangles with the left-handed Milone (4.71 ERA, 1.43 WHIP in 2016) and a Twins squad that is tied for 29th in the Majors with a .670 defensive efficiency ratio.
Josh Donaldson: Since joining the Blue Jays at the outset of 2015, the third baseman has posted a game-changing .320/.428/.631 slash line against left-handers and a .331/.414/.641 slash line at his hitter-friendly home park. Donaldson could thrive in a home matchup against Mariners southpaw Wade Miley, who has recorded a 4.59 ERA and a 1.40 WHIP since the outset of 2014.
Troy Tulowitzki: With an impressive lifetime .315/.399/.548 slash line against left-handers, the shortstop will be in great position to rip his 17th roundtripper of the season when he tangles with the left-handed Miley (5.36 ERA, 1.5 HR/9 in 2016).
Paul Goldschmidt: With a lifetime .336/.437/.604 slash line against left-handers, the first baseman has proven to wield a potent bat in those matchups. Goldschmidt could post a memorable DraftKings total when he bats at hitter-friendly Great American Ball Park against Reds southpaw Brandon Finnegan (career 4.18 ERA, 1.34 WHIP).
Welington Castillo: The catcher owns a lifetime .871 OPS against left-handers that exceeds his .680 mark vs. righties. Castillo could provide production at a premium position when he bats at Cincinnati's hitter-friendly venue against the left-handed Finnegan (4.66 ERA, 1.42 WHIP in 2016) and a Reds relief corps that ranks last in baseball with a 5.43 ERA.
Yasmany Tomas: Since arriving to the Majors at the outset of 2015, the outfielder has posted an .867 OPS against left-handers that far exceeds his .667 mark vs. righties. Set to bat at Cincinnati's homer-happy venue, Tomas could display his power or drive in multiple runs when he faces the left-handed Finnegan (career 5.18 FIP) and an unreliable Reds relief corps.
Adam Eaton: From a premium lineup spot, the outfielder could reach base often or score multiple runs when he brings his lifetime .775 OPS against right-handers (.720 vs. lefties) into a matchup with righty Anibal Sanchez (6.60 ERA, 1.64 WHIP in 2016) and a Tigers bullpen that ranks 23rd in the Majors with a 4.41 ERA.
Danny Espinosa: The shortstop -- who has hit 15 homers across 165 at-bats since May 26 -- could excel when he brings his lifetime .801 OPS against left-handers (.666 vs. righties) into a matchup with left-hander Christian Friedrich (career 5.45 ERA, 1.59 WHIP) and a Padres bullpen that ranks 25th in the Majors with a 4.51 ERA.
Jayson Werth: The outfielder could reach base often or score multiple runs when he takes his lifetime .934 OPS against left-handers (.783 vs. righties) into a matchup with the left-handed Friedrich (4.55 ERA, 1.56 WHIP in 2016) and an unreliable Padres bullpen.
Carlos Gonzalez: In his career, Gonzalez has excelled when facing right-handers (.306/.370/.565 slash line) and when batting at his hitter-friendly home park (.335/.393/.631 slash line). The outfielder could thrive in a home matchup against rookie righty Tyrell Jenkins (4.05 ERA, 1.55 WHIP) and a Braves bullpen that ranks 21st in the Majors with a 4.30 ERA.
Charlie Blackmon: Hitting leadoff, the outfielder could reach base often when he brings his lifetime .804 OPS against right-handers (.729 vs. lefties) into a matchup with the inexperienced righty Jenkins (20 career innings). Blackmon could also swipe a base against catcher A.J. Pierzynski, who sometimes struggles to thwart would-be basestealers.
Jason Kipnis: The second baseman could reach base often or score multiple runs when he brings his lifetime .821 OPS against right-handers (.661 vs. lefties) into a matchup at hitter-friendly Camden Yards against righty Vance Worley (4.03 ERA, 1.46 WHIP since the outset of 2012).
A.J. Griffin: The fly-ball-prone righty will be in great position to have a stellar start when he brings his lifetime 3.71 ERA into a matchup at pitcher-friendly Kauffman Stadium against a Royals lineup that ranks last in the American League with 83 home runs.
Jameson Taillon: Having produced a 3.44 ERA and a 1.18 WHIP across his initial six Major League starts, the right-hander is showing that he can handle big league lineups. Taillon could have his best start to date when he works at home against a Phillies lineup that ranks 28th in the Majors with a .689 OPS against righties.
Jesse Hahn: With a 6.49 ERA this season, the right-hander could have a reduced price tag in DraftKings contests for a matchup at his pitcher-friendly home park against a Rays lineup that ranks 23rd in the Majors with a .706 OPS vs. righties.
All statistics are accurate through the completion of Friday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB. This story was not subject to the approval of Major League Baseball or its clubs.