The players listed below are in position to provide difference-making stats for DraftKings participants on Tuesday.
Miguel Cabrera: With a lifetime .312/.425/.549 slash line against left-handers, the first baseman has proven to be one of the best in baseball during those matchups. Cabrera could post a substantial DraftKings total when he faces southpaw Tommy Milone (career 4.05 ERA, 1.31 WHIP) and a Twins bullpen that ranks 24th in baseball with a 4.43 ERA.
Jose Iglesias: With a lifetime .777 OPS against left-handers that exceeds his .648 mark vs. righties, the shortstop will be in great position to provide cost-effective production when he faces the left-handed Milone (5.09 FIP in 2016) and an unreliable Twins bullpen.
Ian Kinsler: Hitting leadoff, the second baseman may maximize his opportunities to reach base and score runs when he brings his lifetime .885 OPS against left-handers (.764 vs. righties) into a matchup with the left-handed Milone (5.23 ERA, 1.57 WHIP in 2016) and an unreliable Twins bullpen. Kinsler could also swipe a base against catcher Kurt Suzuki, who sometimes struggles to thwart would-be base stealers.
James McCann: As a big leaguer, the catcher has posted an .851 OPS against left-handers in comparison to a .559 mark vs. righties. McCann could provide cost-effective production at a premium position when he faces the left-handed Milone and a Twins squad that ranks last in baseball with a .666 defensive efficiency ratio.
David Ortiz: As a big leaguer, the slugger has posted a .983 OPS against right-handers that exceeds his .813 mark vs. lefties. Ortiz could add to his impressive 2016 totals of 22 homers and 72 RBIs across 303 at-bats when he tangles with Giants righty Jake Peavy (5.09 ERA, 1.45 WHIP in 2016).
Nolan Arenado: In his career, the third baseman has fared best when facing left-handers (.292/.362/.518 slash line) and batting at his offense-inducing home park (.307/.351/.570 slash line). Arenado could post a game-changing DraftKings total when he hits at home against Rays rookie southpaw Blake Snell (1.58 WHIP).
DJ LeMahieu: With balanced career splits and a lifetime .818 OPS at his hitter-friendly home park, the second baseman could provide production from his premium position at the expense of the inexperienced Snell and a Rays relief corps that ranks 27th in the Majors with a 4.68 ERA.
Trevor Story: Having tied a National League rookie record with 21 first-half long balls, the shortstop has been a major factor in many 2016 DraftKings contests. Set to bat at his homer-happy home park, Story could improve on his .900 OPS against left-handers (.859 vs. righties) when he faces the inexperienced southpaw Snell and an unreliable Rays relief corps
Chris Davis: The left-handed-hitting first baseman will be poised to drive in multiple runs or hit his 23rd homer of the season when he bats at hitter-friendly Yankee Stadium against righty Nathan Eovaldi (career 4.24 ERA, 1.39 WHIP). Also working in Davis' favor: New York's venue has proven to be especially homer-happy for lefty batters.
Matt Adams: The first baseman has long fared best vs. right-handers, against whom he has a lifetime .816 OPS (.574 vs. lefties). Adams could go deep or drive in multiple runs when he faces righty Colin Rea (career 4.76 ERA, 1.39 WHIP) and a Padres bullpen that ranks 23rd in the Majors with a 4.35 ERA.
Aledmys Diaz: Hitting .313 with 13 homers across 304 at-bats, the rookie shortstop has been a major contributor to many 2016 DraftKings squads. Diaz could improve on his .949 OPS against right-handers (.829 vs. lefties) when he faces the right-handed Rea (4.95 ERA, 1.43 WHIP in 2016) and a Padres squad that ranks 26th in baseball with a .678 defensive efficiency ratio.
Jay Bruce: The outfielder could add to his 2016 totals of 18 homers and 64 RBIs across 325 at-bats when he bats at his hitter-friendly home park against Braves rookie righty Tyrell Jenkins (4.50 ERA, 1.64 WHIP). In his career, Bruce has logged an .814 OPS against right-handers in comparison to a .720 mark vs. lefties.
Joey Votto: The first baseman has used a patient, powerful approach to build a lofty lifetime .314/.433/.543 slash line against right-handers. Votto could rip a round-tripper or reach base often when he faces the inexperienced righty Jenkins (14 career innings) and a Braves bullpen that ranks 20th in baseball with a 4.18 ERA.
Nomar Mazara: The rookie outfielder will be in great position to improve on his solid .295/.351/.464 slash line against right-handers when he faces Angels righty Tim Lincecum (4.76 ERA, 1.43 WHIP since the outset of 2012).
Carlos Martinez: With a 2.95 ERA since the outset of 2015, the right-hander has become one of the most reliable starters in the National League. Martinez could continue to hold the opposition in check when he works at his pitcher-friendly home park against a Padres lineup that ranks 29th in the Majors with a .672 OPS against righties.
Danny Salazar: Having posted a 3.20 ERA, a 1.15 WHIP and a 9.7 K/9 rate since the outset of 2015, the right-hander ranks among the most dominant starters in the American League. Salazar has the skills to spin a gem when he faces a Royals lineup that ranks 21st in the Majors with a .711 OPS against righties.
Cody Reed: With an 8.39 ERA and a 1.86 WHIP across five starts, the rookie left-hander could have a reduced price tag in DraftKings contests when he faces a Braves lineup that ranks 29th in baseball in OPS vs. lefties (.641) and last in total home runs (56).
All statistics are accurate through the completion of Sunday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.