The players listed below are in position to provide difference-making stats for DraftKings participants on Saturday.
Xander Bogaerts: Hitting .329 with 56 RBIs and 65 runs across 394 plate appearances, the shortstop has been one of the most productive players at his premium position this season. Bogaerts has the plate skills to thrive against Yankees southpaw CC Sabathia (4.63 ERA, 1.39 WHIP since the outset of 2013) and the speed to swipe a base against Brian McCann, who has allowed more steals than all but two catchers in 2016.
Dustin Pedroia: The second baseman has long fared best vs. left-handers, against whom he has a lifetime .844 OPS (.795 vs. righties). Pedroia could post a notable DraftKings total when he hits in the No. 2 spot in a talented Red Sox lineup against the left-handed Sabathia at hitter-friendly Yankee Stadium.
Ryan Braun: With a lifetime .335/.404/.624 slash line against left-handers, the outfielder has proven to be one of the best in baseball during those matchups. Braun could post a substantial DraftKings total when he bats at hitter-friendly Great American Ball Park against Reds southpaw John Lamb (career 5.58 ERA, 1.54 WHIP).
Jonathan Lucroy: The catcher could provide elite production at a premium position when he brings his lifetime .828 OPS against left-handers (.763 vs. righties) into a matchup with the left-handed Lamb (5.43 ERA, 1.53 WHIP in 2016) and a Reds relief corps that ranks last in baseball with a 5.70 ERA.
Jonathan Villar: With a lifetime .751 OPS against left-handers that exceeds his .687 mark vs. righties, the shortstop has the plate skills to reach base several times vs. the southpaw Lamb and an unreliable Reds bullpen. Villar could also add to his Major League-leading total of 31 steals at the expense of Tucker Barnhart, who has surrendered more swipes than any other catcher in 2016.
Carlos Gonzalez: With an impressive lifetime .936 OPS against right-handers that exceeds his .747 mark vs. lefties, the outfielder could post a difference-making DraftKings total when he faces Braves righty Mike Foltynewicz (career 5.02 ERA, 1.50 WHIP). In his career, Foltynewicz has allowed left-handed hitters such as Gonzalez to tally a .964 OPS (.779 OPS allowed to righty batters).
Freddie Freeman: With a lifetime .880 OPS against right-handers that exceeds his .755 mark vs. lefties, the first baseman will be poised to produce when he faces righty Chad Bettis (career 5.37 ERA, 1.54 WHIP) and a Rockies squad that ranks 29th in the Majors with a .670 defensive efficiency ratio.
Nick Markakis: As a big leaguer, the outfielder has produced an .809 OPS against right-handers in comparison to a .725 mark vs. lefties. From a premium lineup spot, Markakis could reach base often or drive in multiple runs when faces the right-handed Bettis (5.65 ERA, 1.50 WHIP in 2016) and a Rockies bullpen that ranks 29th in the Majors with a 5.09 ERA.
Eric Hosmer: Hitting .299 with 13 homers and 49 RBIs across 334 at-bats, the first baseman has been a major contributor on many 2016 DraftKings squads. Hosmer could continue to excel when he brings his lifetime .807 OPS against right-handers (.698 vs. lefties) into a matchup with righty Mike Pelfrey (4.58 ERA, 1.71 WHIP in 2016) and a Tigers bullpen that ranks 26th in the Majors with a 4.53 ERA.
Kendrys Morales: In his career, the slugger has logged an .812 OPS against right-handers that exceeds his .750 mark vs. lefties. Morales -- who is hitting .423 with eight homers and 23 RBIs across 71 at-bats since June 17 -- could go deep or drive in multiple runs when he tangles with the right-handed Pelfrey (career 4.52 ERA, 1.50 WHIP) and an unreliable Tigers bullpen.
Mike Trout: With a lifetime .312/.400/.573 slash line against right-handers, the outfielder has proven to wield a potent bat during those matchups. Trout could put a ball into the outfield seats when he faces White Sox righty James Shields (5.42 ERA, 1.60 WHIP, 1.6 HR/9 rate in 2016).
Kole Calhoun: With a lifetime .773 OPS against right-handers that exceeds his .738 mark vs. lefties, the outfielder will be poised to rip a round-tripper or drive in multiple runs when he tangles with the right-handed Shields. The righty hurler owns a 7.68 ERA and a 1.94 WHIP across seven starts as a member of the White Sox.
Jake Lamb: Hitting .291 with 20 homers and 61 RBIs across 289 at-bats, Lamb is in the midst of a breakout season. The third baseman could post a notable DraftKings total when he works at his hitter-friendly home park against Dodgers righty Brandon McCarthy (career 4.12 ERA, 1.29 WHIP), who will be making his third start since returning from Tommy John surgery.
Matt Shoemaker: With a 2.67 ERA, a 1.08 WHIP and a 10.0 K/9 rate across his past 10 starts, the right-hander has been a major contributor to many recent DraftKings squads. Shoemaker could stay hot when he works at his pitcher-friendly home venue against a White Sox lineup that ranks 24th in the Majors with a .708 OPS against righties.
Chris Tillman: The right-hander could improve on his solid 2016 numbers (12-2 record, 3.41 ERA, 1.23 WHIP) when he vacates his hitter-friendly home park and works at offense-suppressing Tropicana Field against a Rays lineup that ranks 26th in the Majors with a .700 OPS against righties.
Jeff Samardzija: Having logged a 6.02 ERA since May 30, the right-hander could have a reduced cost in DraftKings contests when he brings his solid 3.91 ERA this season into a matchup at pitcher-friendly Petco Park against a Padres lineup that ranks 29th in baseball with a .665 OPS against righties.
Logan Verrett: Set to replace Matt Harvey in the Mets' rotation, the right-hander could be a cost-effective second starter in DraftKings contests when he faces a Phillies lineup that ranks 25th in the Majors with a .707 OPS against righties.
All statistics are accurate through the completion of the All-Star break.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.