MLB.com Columnist

Fred Zinkie

Tigers trio could feast vs. White Sox southpaw

Dodgers' Maeda, Brewers' Nelson in good position for strong outings

Tigers trio could feast vs. White Sox southpaw

Welcome to DraftKings fantasy baseball, the Official Daily Fantasy Game of Major League Baseball.

The players listed below could provide difference-making stats for DraftKings participants on Friday.

John Jaso: The first baseman has long fared best vs. right-handers, against whom he has a lifetime .800 OPS (.532 vs. lefties). Hitting leadoff, Jaso may maximize his chances to succeed against Angels righty Jered Weaver (4.85 ERA since the outset of 2015).

Jung Ho Kang: Hitting out of the cleanup spot, the third baseman -- who has hit six homers across 65 at-bats this season -- could display his power when he brings his balanced career splits into a matchup with the fly-ball-prone Weaver (1.5 HR/9 rate since the outset of 2015).

Danny Espinosa: Hitting .200 this season, the shortstop could have a reduced DraftKings price tag when he brings his solid lifetime .781 OPS against left-handers (.657 vs. righties) into a matchup at hitter-friendly Great American Ball Park against Reds southpaw Brandon Finnegan (4.14 ERA, 1.38 WHIP in 2016).

Jayson Werth: Expected to hit out of a premium lineup spot, the outfielder could display his power or reach base several times when he takes his lifetime .931 OPS against southpaws (.784 vs. righties) into a matchup with the left-handed Finnegan (career 4.76 FIP). Werth could also thrive late in the game against a Reds relief corps that ranks last in the Majors with a 6.69 ERA.

Michael Conforto: The second-year outfielder has posted lopsided splits, with a .914 OPS against right-handers that exceeds his .313 mark vs. lefties. Conforto could drive in multiple runs when he tangles with Marlins righty Tom Koehler (career 4.14 ERA, 1.37WHIP).

Neil Walker: With 13 homers across 180 at-bats, the second baseman has been one of the most powerful players at his premium position this season. Walker could excel when he brings his lifetime .800 OPS against right-handers (.684 vs. lefties) into a matchup with the right-handed Koehler (4.50 ERA, 1.65 WHIP in 2016).

Corey Dickerson: Hitting .204 this season, the outfielder could have a reduced price tag in DraftKings contests when he brings his impressive lifetime .916 OPS against right-handers (.617 vs. lefties) into a matchup with Twins righty Ricky Nolasco (5.56 ERA, 1.49 WHIP since the outset of 2014). Also of note: Dickerson will attempt to put balls into play against a Twins squad that ranks last in the Majors with a .660 defensive efficiency ratio.

David Ortiz: In his legendary career, the slugger has posted an impressive .294/.397/.583 slash line against right-handers. Ortiz -- who is hitting .339 with 15 homers and 48 RBIs across 180 at-bats this season -- will be poised to display his power when he faces right-hander R.A. Dickey, who has posted a 4.01 ERA and a 1.2HR/9 rate since joining the Blue Jays at the outset of 2013.

Travis Shaw: The third baseman will be in prime position to improve his lifetime .283/.353/.485 slash line against right-handers when he tangles with the right-handed Dickey (4.64 ERA, 1.32 WHIP in 2016). Shaw may be part of a productive lineup Friday, as the Red Sox lead the Majors in runs scored (317) and OPS vs. righties (.853).

Ian Kinsler: From his perch atop the lineup, the second baseman could reach base often and score multiple runs when he brings his lifetime .886 OPS against left-handers (.763 vs. righties) into a matchup with southpaw Carlos Rodon (4.24 ERA, 1.48 WHIP in 2016). In his career, Rodon has allowed right-handed hitters such as Kinsler to post an .803 OPS (.531 OPS allowed to lefty batters). Kinsler could also swipe a base Friday, as White Sox catchers Dioner Navarro and Alex Avila have combined to throw out six of 35 would-be basestealers in 2016.

Jose Iglesias: The right-handed-hitting shortstop could provide cost-effective production at a premium position when he brings his lifetime .758 OPS against left-handers (.640 vs. righties) into a matchup with Rodon (career 1.45 WHIP). Iglesias could be part of a Tigers stack -- including Kinsler, Castellanos and outfielder J.D. Martinez -- against the lefty hurler.

Kenta Maeda: With a 3.00 ERA and a 1.05 WHIP, the first-year right-hander is off to a solid start in the Majors. Maeda could post an impressive total in DraftKings contests when he works at home against a Braves lineup that ranks last in the Majors in OPS against righties (.626) and total home runs (22).

Danny Salazar: With a 3.19 ERA, a 1.13 WHIP and a 9.8 K/9 rate since the outset of 2015, the right-hander has the skills to handle a Royals lineup that ranks last in the American League with 44 long balls and will operate without injured regulars Alex Gordon and Mike Moustakas.

Francisco Liriano: Having produced a 4.63 ERA and a 1.49 WHIP this season, the left-hander could have a reduced price tag in DraftKings contests when he works at his pitcher-friendly home park against an Angels lineup that ranks 27th in the Majors with a .656 OPS against southpaws.

Jimmy Nelson: With a 2.88 ERA and a 1.17 WHIP, the right-hander has emerged as the Brewers' most reliable starter this season. Nelson could have a stellar start when he faces a Phillies lineup that ranks 28th in the Majors with a .655 OPS against righties.

All statistics are accurate through the completion of Wednesday's games.

Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB This story was not subject to the approval of Major League Baseball or its clubs.