SAN DIEGO -- Apparently eager to put a rough road trip behind them, the Padres wasted no time pouncing on Mariners spot starter James Paxton in their return to Petco Park on Wednesday night. They put six runs on the board in the first, kicked the extra point in the second and finished with a 14-6 victory over their Pacific Northwest foes.
Alexei Ramirez led the way with a pair of homers -- his first two as a Padre at Petco Park -- and a career-high five RBIs. Wil Myers, who finished a triple shy of the cycle, and Adam Rosales also went deep. The 19 hits for the Padres matched a season high, and the 14 runs were the most they've scored in a home game this season.
"It was a disappointing [1-7] road trip," said Padres skipper Andy Green. "You get back home, it's a welcome environment to be back in. I think what it was was a great response to the three runs we gave up in the first inning."
Robinson Cano took Padres starter Christian Friedrich deep in the top of the first inning, giving the Mariners that three-run lead before an out was recorded. But Friedrich settled in nicely after that, tossing five frames while allowing only those three earned runs and another unearned run in the fourth.
"We had just picked up the bullpen phone," Green said of Friedrich escaping the 37-pitch first inning. "That's right where we were. He's upper-30s in pitches, but we're trying to give him a lot more leash than you typically do, considering [the bullpen being used a lot] yesterday. You don't want to run through the bullpen in the second inning."
Paxton wasn't quite as adept at limiting the damage. Filling in for Felix Hernandez -- who hit the disabled list Wednesday afternoon -- Paxton allowed eight runs (only three of them earned) on 10 hits in 3 2/3 frames.
"It's disappointing," said Paxton, who was 12-8 with a 3.16 ERA in 30 starts over the previous three years. "I was just too amped up, too fired up for it. I was just going too fast."
MOMENTS THAT MATTERED Padres make 'em pay: Following Myers' solo homer, the Padres tacked on five more runs in the opening frame -- all of them unearned. On a tapper back to the mound, Paxton threw the ball into center field attempting to get a forceout at second base. Derek Norris would then tie the game with a sac fly, and Ramirez gave the Friars the lead with an RBI single, before Rosales put a capper on the frame with a two-run blast into the left-field seats.
"They scored three right away, and I'm like, 'All right, we've got to answer back,'" Rosales said. "We did, scoring six runs in one inning. We just took the momentum from there on out." More >
Cano keeps crankin': The Mariners' second baseman gave Seattle a 3-0 lead in the first with his 16th homer of the season, a line-drive shot just over the right-field fence that got out in a hurry -- with a 110-mph exit velocity, per Statcast™. Cano now is one back of the White Sox's Todd Frazier for the Major League home run lead and tied with the Red Sox's David Ortiz for the most RBIs, with 48. It took Cano 137 games last year to reach 16 homers. This year, he's there in 52. But the Mariners weren't able to build on that early start.
"Robbie jumps on a big first-pitch fastball, and we had a chance to get more," said Mariners skipper Scott Servais of the first inning. "Unfortunately we weren't able to add on. We probably could have had four or five in that inning.
"I thought we were in a great spot, but the game is driven by starting pitching. That's why we've gotten to the point we're at. We've been very consistent with guys going out there and giving us a chance to win games."
Alexei powers up: In five of Ramirez's first eight big league seasons, he recorded at least 15 homers. The Padres' shortstop struggled to find that power stroke early this season and didn't hit his first dinger with the Padres until Sunday in Arizona. But Ramirez has now gone deep three times in four days, after he recorded the second two-homer game of his career on Wednesday night. He also did so as a member of the White Sox on April 12, 2011, against the A's.
"I'm still learning every day," Ramirez said. "I spent my whole career up until now in the American League. Now, in the National League, I'm still learning pitchers, still learning everyone, getting to know them. I think that's a big part of it. Aside from that, it's just seeing the ball well." More >
New month, same results: Mariners third baseman Kyle Seager was one of the hottest hitters in baseball in May, and he turned the calendar page to June without slowing down, going 4-for-5 and scoring twice. Seager is 45-for-117 (.385) since April 30 with six homers and 24 RBIs, hiking his average from .139 to .287.
"We beat them at our place by almost the same score. They came back today and got mad maybe. You have to give them credit, the way they swung the bat. Paxton was throwing 98 [mph]. He's tough. Even lefties were able to get hits. We got beat. Nothing else you can do." -- Cano, on the Mariners' loss
"I don't slow down. He's got to speed up." -- Rosales, on nearly passing Ramirez on the bases during his home run "trot"
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In his first two at-bats, Myers hit a pair of lasers -- one into the right-center-field seats that was tracked by Statcast™ at 106 mph, and one a single to right that Statcast™ clocked at 100 mph. Entering Wednesday, Myers had recorded two triple-digit exit velocities in the previous 10 days combined.
A day after racking up their season high in runs in a 16-4 rout of the Padres in Seattle, the Mariners gave up their most runs in a game this season on Wednesday night. Their previous high allowed was nine, to the Angels in a 9-7 loss on May 14.
WHAT'S NEXT Mariners:Wade Miley (5-2, 4.95 ERA) closes out the Interleague series at Petco Park in Thursday's 6:10 p.m. PT start, looking to bounce back from a rough outing against the Twins when he allowed three homers in four-plus innings in a no-decision. The lefty is 1-6 with a 4.60 ERA in 12 career starts against the Padres.
Padres:Colin Rea (3-2, 4.47 ERA) makes his return to the Padres after a brief stint in the Minors, and he'll face the Mariners on Thursday in the last of four games between the clubs this week. First pitch is set for 6:10 p.m. PT.
Greg Johns has covered the Mariners since 1997, and for MLB.com since 2011. Follow him on Twitter @GregJohnsMLB and listen to his podcast. This story was not subject to the approval of Major League Baseball or its clubs.