"I think he could play if he had to, but we've got to make sure what's going on there," Molitor said. "It's been bothering him for a little bit, but he's been treating it and he's been doing pretty well. I think tonight, for whatever reason, he felt a little increase in the pain and lack of mobility, so we had to get him out of the game."
Plouffe started the game at Safeco Field at third base and had two at-bats, striking out in the second inning and flying out to center in the middle of his team's five-run third.
When the Twins took the field in the bottom of the fourth inning, however, starting shortstop Eduardo Nunez had moved to third base and Eduardo Escobar had entered to play shortstop.
Doug Miller is a reporter for MLB.com. Follow him on Twitter @DougMillerMLB. This story was not subject to the approval of Major League Baseball or its clubs.