After hobbling to take his base and staying in the game for the rest of the half-inning, Ramirez was replaced by Travis Shaw on defense to start the fifth.
This was the first game this season regular third baseman Shaw wasn't in the starting lineup, but his downtime was short-lived.
Ian Browne has covered the Red Sox for MLB.com since 2002. Follow him on Twitter @IanMBrowne and Facebook. This story was not subject to the approval of Major League Baseball or its clubs.