Saupold replaced left-handed pitcher Daniel Norris, who was sent back to Toledo after being recalled Wednesday.
"He started on Monday, so he can give us innings," Tigers manager Brad Ausmus said of the Perth, Australia, native.
Norris pitched one inning Thursday as the last of five relievers to face Baltimore in Detroit's ninth loss in 10 games.
Saupold is 3-1 with a 2.37 ERA and 14 strikeouts in 30 1/3 innings for Toledo this season. Now in his fifth season, he is 28-29 with a 3.87 ERA in the Minors.
"[Former Tigers manager] Jim Leyland has talked about him for a couple years," Ausmus said. "He really likes him. ... We'll find out."
Ben Standig is a contributor to MLB.com based in Baltimore. This story was not subject to the approval of Major League Baseball or its clubs.