The players listed below could provide difference-making stats for DraftKings participants on Monday.
Carlos Beltran: With balanced career splits that include a .280/.357/.483 slash line against right-handers, the outfielder could hit a homer at Yankee Stadium when he faces Royals fly-ball-prone righty Chris Young (career 1.2 HR/9 rate). The switch-hitting Beltran will bat from the left side against Young, and Yankee Stadium has proven to be especially homer-enhancing for lefty batters.
Brian McCann: In his career, the left-handed-hitting catcher has logged an .824 OPS against right-handers that exceeds his .754 mark against lefties. McCann -- who has hit 29 homers across 544 at-bats since the outset of 2015 -- could provide power from a premium position when he bats at his homer-happy home park against the long-ball-prone righty Young. In his career, Young has allowed left-handed hitters such as McCann to post a .720 OPS (.658 OPS allowed to righty batters).
Adam Eaton: From his perch atop the lineup, the outfielder will be poised to reach base often and score multiple runs when he brings his lifetime .779 OPS against right-handers (.719 vs. lefties) into a matchup at hitter-friendly Globe Life Park in Arlington against righty Colby Lewis (career 4.76 ERA, 1.37 WHIP). As a big leaguer, Lewis has allowed left-handed hitters such as Eaton to post an .817 OPS (.729 OPS allowed to righty batters).
John Jaso: Jaso has registered notable career splits, with a .796 OPS against right-handers that exceeds his .547 mark vs. lefties. The first baseman -- who owns a lifetime .361 on-base percentage -- could reach often or drive in multiple runs when he faces righty Dan Straily (career 4.49 ERA, 1.29 WHIP) at hitter-friendly Great American Ball Park.
Gregory Polanco: Polanco has registered pronounced career splits, with a .764 OPS against right-handers in comparison to a .524 mark vs. lefties. The speedy outfielder could produce in multiple ways when he faces the right-handed Straily (career 4.79 FIP) at Cincy's hitter-friendly venue. He could also succeed late in the game against a Reds relief corps that ranks 30th in the Majors with a 6.57 ERA.
Derek Dietrich: Recently tabbed as Miami's starting second baseman, Dietrich could provide power from a premium position when he brings his lifetime .789 OPS against right-handers (.611 vs. lefties) into a matchup with righty Wily Peralta (career 4.21 ERA, 1.42 WHIP) and a Brewers bullpen that ranks 25th in the Majors with a 4.61 ERA. Also of note: Milwaukee sits 28th in the big leagues with a .665 defensive efficiency ratio.
Christian Yelich: Hitting .343, the outfielder has been a notable contributor to many 2016 DraftKings squads. With a lifetime .819 OPS against right-handers (.702 vs. lefties), the outfielder has the plate skills to reach base often against Peralta (7.50 ERA, 1.93 WHIP in 2016). Yelich also possesses the speed to swipe a base against Jonathan Lucroy, who has allowed more steals than any other catcher in 2016.
Carlos Gonzalez: In his career, Gonzalez has fared best when facing right-handers (.304/.368/.564 slash line) and when batting at hitter-friendly Coors Field (.330/.390/.619 slash line). Gonzalez could provide a notable total in DraftKings contests when he hits at home against D-backs righty Archie Bradley (lifetime 6.30 ERA, 1.73 WHIP).
Gerardo Parra: Parra has long fared best vs. right-handers, against whom he has registered a lifetime .764 OPS (.610 vs. lefties). The outfielder could excel against the right-handed Bradley, who will be making his second start of the year after allowing five runs on seven hits and four walks over 4 1/3 innings in his first outing.
Jake Lamb: Since making his big league debut in 2014, the third baseman has produced a .753 OPS against right-handers that dwarfs his .560 mark vs. lefties. Lamb could drive in multiple runs when he faces the righty Chatwood (career 4.48 FIP) and a shaky Rockies bullpen at hitter-friendly Coors Field.
Addison Russell: Since making his big league debut early in the 2015 season, the shortstop has recorded a .753 OPS against right-handers that exceeds his .517 mark vs. lefties. Russell could provide production at a premium position when he tangles with Padres righty Cesar Vargas, who will be making his fourth big league start (4.37 FIP in first three).
Jose Fernandez: With a lifetime 2.59 ERA, 1.05 WHIP and 10.7 K/9 rate, the right-hander is among the most dominant starters in the Senior Circuit. Fernandez could combine six-plus quality innings with a handful of strikeouts and a win when he works at his pitcher-friendly home park in a seemingly advantageous matchup with the Brewers' Peralta.
Steven Matz: The left-hander will be poised to post a notable total in DraftKings contests when he brings his impressive lifetime 2.52 ERA into a matchup with the Dodgers at their pitcher-friendly home park. Working in Matz's favor is the fact that the Dodgers rank 17th in the Majors with a .718 OPS against southpaws.
Jon Lester: With a 3.05 ERA and a 1.11 WHIP since joining the Cubs at the outset of 2015, the left-hander has proven to be among the most effective starters in the Senior Circuit. Lester could post a difference-making total in DraftKings contests when he works at home against a Padres lineup that sits 13th in the National League with 113 runs scored and second in the Majors with 292 whiffs. Also of note: Lester will be backed by a Cubs squad that leads baseball by a wide margin with a .740 defensive efficiency ratio.
Corey Kluber: With a 2.98 ERA, a 1.06 WHIP and a 10.0 K/9 rate since the outset of 2014, the right-hander is among the most effective starters in the Junior Circuit. Kluber may be worth a major expenditure in DraftKings contests when he faces an Astros lineup that leads the Majors with 298 strikeouts.
All statistics are accurate through the completion of Saturday's games.
Fred Zinkie is the lead fantasy baseball writer for MLB.com. Follow him on Twitter at @FredZinkieMLB. This story was not subject to the approval of Major League Baseball or its clubs.