Trevor Plouffe led the Twins' offensive attack, going 2-for-2, with a walk, four RBIs and one run scored. Plouffe's big hit was a three-run home run in the Twins' four-run second inning in which they sent eight batters to the plate.
"I feel good," Plouffe said of his spring. "I think we're showing that we have a pretty potent lineup and can put up some runs. I think that our pitching has been great, too. I'm happy with how things are going. For the most part, we're healthy, and that's really the main thing that you want to get through Spring Training. So we're excited about the year."
Twins right-hander Ricky Nolasco, competing for a spot in the rotation, made his third appearance and second start of the spring. He went three innings, giving up three runs on four hits and two walks with two strikeouts.
"I feel good, arm feels good," Nolasco said. "Started rushing a little bit there with all those walks, but for the most part thought I made some good pitches, got some ground balls, missed a few good pitches."
It's been a rough spring so far for Orioles starter Miguel Gonzalez, who has allowed at least six runs in two of his three starts. Making his third Grapefruit League start, Gonzalez lasted just 1 2/3 innings, giving up six runs on seven hits and three walks with two strikeouts and a home run. Overall, he has surrendered 14 runs on 18 hits over just 5 2/3 innings.
"I was just off a little bit," Gonzalez said. "Flying open. I wasn't consistent down, ahead. That's important. Guys are being aggressive. I've just got to try not to do too much out there. I wouldn't change anything.
"Things are not going my way right now, and all I've got to do is keep working hard and don't get down. Keep my head up, and hopefully my next time out I'll be all right."
Christian Walker went 2-for-3 for Baltimore, with a solo home run to lead off the fifth.
Eddie Rosario went 2-for-3 with an RBI for the Twins, while James Beresford, who entered as a pinch runner for Plouffe, went 2-for-3 with two RBIs and two runs scored.
Up next for the Orioles: The Orioles return home to Ed Smith Stadium on Monday to host the Phillies at 1:05 p.m. ET, live on Gameday Audio. Right-hander Yovani Gallardo will make his second start in a Baltimore uniform after debuting against Philadelphia last Wednesday, when he allowed three runs on four hits over two innings.
Up next for the Twins: Left-hander Tommy Milone will make his third Grapefruit League start on Monday when the Twins travel to Jupiter, Fla., to face the Cardinals at 1:05 p.m. ET. The game will air on MLB.TV and an exclusive free webcast. Right-hander Mike Leake gets the start for St. Louis.
Maureen Mullen is a contributor for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.