Roberts said Kendrick first felt discomfort during drills on Sunday, felt better Monday morning, but was scratched after he tried doing drills again before Monday's game.
Rob Segedin replaced Kendrick at third base and Shawn Zarraga took over for Segedin as designated hitter. Segedin had an RBI double and walked in three plate appearances on Monday.
Kendrick, 32, was signed to a two-year, $20 million contract last month after finding a lukewarm reception on the free-agent market. He hit .295 last year for the Dodgers, but also spent five weeks on the disabled list with a strained left hamstring.
Ken Gurnick is a reporter for MLB.com. Listen to his podcast. This story was not subject to the approval of Major League Baseball or its clubs.