Not only did the National League win, 4-3, in dramatic fashion to end the American League's four-year winning streak, it was the first All-Star Game to go into extra innings and included some of the greatest pitching performances in All-Star Game history.
St. Louis Cardinals second baseman Red Schoendienst tipped the scales in favor of the NL when he led off the 14th inning with a home run off Detroit Tigers pitcher Ted Gray.
The NL appeared headed to a fifth straight defeat when Pittsburgh Pirates left fielder Ralph Kiner led off the ninth with a tape-measure homer off Art Houtteman of the Tigers to tie the game.
With the NL trailing, 3-2, New York Giants right-hander Larry Jansen entered the game in the bottom of the seventh and held the AL scoreless over five innings, allowing one hit and no walks with six strikeouts.
Ewell "The Whip" Blackwell of the Cincinnati Reds took over in the 12th and held the AL to one hit and no walks with two strikeouts over the final three scoreless innings to get the win. The AL was blanked on only two hits and no walks over the final nine innings while striking out 10 times.
Allie Reynolds went head-to-head with Jansen and Blackwell, holding the National League to a hit and a walk in three scoreless innings until giving way to Gray in the 13th.
Schoendienst had entered the game in the 11th as a replacement for starting second baseman Jackie Robinson of the Los Angeles Dodgers. The game played on July 11 at Comiskey Park in Chicago didn't start out as a pitching duel.
The NL took a 2-0 lead in the top of the second against AL starter Vic Raschi of the Yankees. Robinson opened the inning with a single and scored on a triple by Cardinals center fielder Enos Slaughter, who scored on a sacrifice fly by Cubs right fielder Hank Sauer.
The NL wouldn't score again until Kiner's game-tying homer.
The AL got on the board in the third, when Washington Senators second baseman Cass Michaels opened the inning with a ground-rule double off NL starter Robin Roberts of the Philadelphia Phillies, and he scored on a sacrifice fly by Tigers third baseman George Kell.
The AL took a 3-2 lead in the fifth with two runs off the Dodgers' Don Newcombe. Cleveland Indians pitcher Bob Lemon drew a walk to open the inning and moved to third on a one-out double by teammate/center fielder Larry Doby.
Lemon, who allowed one hit in his three scoreless innings, scored on a second fly out by Kell, and Doby scored the go-ahead run on a two-out single by Ted Williams.
It was not, however, a memorable All-Star Game for the San Diego native Williams. The Boston Red Sox left fielder injured suffered an injury to his right elbow while running into the wall when making a running catch of a Kiner drive in the first. Although Williams stayed in the game and went 1-for-4, an examination the following day showed a broken bone.
Williams had surgery and didn't return to the Boston lineup until Sept. 15.
Kiner, Slaughter and Cubs center fielder Andy Pafko each had two of the NL's 10 hits. Yankees shortstop Phil Rizzuto and Doby combined for half the AL's eight hits.
Coleman entered the game in the ninth and struck out in both of his at-bats.