"We were informed that a deal couldn't be pulled together at this time," D-backs spokesperson Shaun Rachau said.
Had the deal gone through, the two teams would have played two exhibition games plus two regular-season games in Taiwan in late March. They then would have returned to Arizona to finish up Spring Training before resuming the regular season.
As part of the deal, the D-backs would have had to give up a pair of home dates against the Giants, which they had indicated they were willing to do.
"We hope that by having gone through this process we will be selected for regular-season games that may be held internationally in coming seasons," Rachau said.
The Giants are scheduled to open the regular season against the Dodgers in Los Angeles on April 1.
The D-backs, meanwhile, will open against the Rockies in Coors Field on April 1.
Steve Gilbert is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.