Starting at 8 p.m. ET tonight, this year's contest will be broadcast live on MLB Network and streamed live on MLB.com. Below is a team-by-team guide to the prospects who will take the AFL's biggest stage:
The No. 1 overall pick in the Rule 5 Draft at the 2014 Winter Meetings, Hernandez offers raw power and a strong arm, but he didn't get to show off his tools much this season. Between jumping from low Class A and injuring the hamate bone in his left hand, he totaled just 69 at-bats.
Sims' mid-90s fastball got him drafted 21st overall in 2012. If he can refine his secondary pitches and his command, he could be a No. 3 starter.
LHP Donnie Hart
Mike Yatrzemski, the grandson of Hall of Famer Carl Yastrzemski, would have had the most famous name in the Fall Stars Game, but he was replaced on the roster on Friday. Hart is a sidearming lefty specialist. The 2013 27th-round pick out of Texas State has posted a 2.26 ERA over three Minor League seasons. He went 6-2 with a 1.49 ERA in 54 1/3 innings across three levels in 2015.
1B Sam Travis
One of the better college hitters in the 2014 Draft, Travis was a second-round pick and hit .307/.381/.452 while reaching Double-A during his first full pro season. He makes consistent hard contact and could hit 15-20 homers per year if he develops a more aggressive approach.
RHP Corey Black, 3B Jeimer Candelario
The Fall Stars Game lost one of the top catching prospects in baseball when Willson Contreras injured his hamstring on Thursday. He was replaced on the roster by Minnesota's Mitch Garver. Candelario is yet another promising young hitter from the Cubs' system, a switch-hitter who can do damage from both sides of the plate. Acquired from the Yankees in the 2013 Alfonso Soriano trade, Black is a reliever with a mid-90s fastball.
OF Adam Engel, RHP Robinson Leyer
Though he's inconsistent at the plate, Engel has some of the best pure tools in the AFL, with well-above-average speed, fine center-field skills and considerable raw power. Leyer is a raw thrower who can reach 98 mph with his fastball.
SS/2B Alex Blandino, OF Phillip Ervin
Blandino (Stanford, 29th overall in 2014) and Ervin (Samford, 27th overall in 2013) were both college first-round choices. A line-drive machine, Blandino is a better defensive fit at second base, where he's playing in Arizona, than at shortstop, his position during his first two years as a pro. Ervin has the potential for at least average tools across the board, but they have yet to translate into production in the Minors.
OF Clint Frazier, RHP Perci Garner
The fifth overall choice in the 2013 Draft, Frazier may have the best bat speed in the AFL -- not to mention huge power potential and solid speed and arm strength. A former quarterback at Ball State, Garner is a middle reliever who relies on his lively low-90s fastball.
RHP Carlos Estevez, LHP Kyle Freeland, OF Raimel Tapia
One of the better pure hitters in the Fall League, Tapia has developing power, solid speed and a chance to remain in center field. Shoulder and elbow issues limited Freeland to 46 2/3 innings in his first full pro season after the Rockies made him the eighth overall choice in the 2014 Draft. He commands his lively 92-96 mph fastball well and backs it up with a promising slider. Estevez, who tops the AFL with four saves, has a fastball that climbs into the upper 90s.
OF Mike Gerber, RHP Adam Ravenelle
An intriguing sleeper, Gerber was a 15th-round senior sign out of Creighton in 2014 and can do a little bit of everything while profiling best in right field. Ravenelle, who saved the championship game of the 2014 College World Series, is a sinker/slider reliever who can hit the mid-90s.
3B J.D. Davis, OF Derek Fisher
Fisher (supplemental first) and Davis (third) had huge first full pro seasons after going early in the 2014 Draft. Fisher hit .275/.364/.483 with 22 homers and 31 steals between two Class A stops, showing off solid hitting ability, power and speed. Davis, who has plus raw power and arm strength, batted .289/.370/.520 with 26 homers and 101 RBI in high Class A.
2B/SS Ramon Torres
A switch-hitter who makes consistent contact from both sides of the plate, Torres projects as a utilityman.
LHP Greg Mahle
The lone player on the Angels' Top 30 Prospects list in Arizona, Mahle is a lefty reliever who mixes four pitches and a variety of arm slots to keep hitters off balance.
RHP Ralston Cash, OF Jacob Scavuzzo
Scavuzzo was a four-sport start at Villa Park (Calif.) High and was named Orange County's male athlete of the year in 2012 before being drafted by the Dodgers in the 21st round. He won the Fall League Hitting Challenge in October. Cash slipped on a muddy mound in his 2010 pro debut after the Dodgers made him a second-round pick, costing him all of 2011, but he has since has progressed to Triple-A. He's a reliever who works mostly with a cutter and low-90s fastball.
OF Austin Dean
One of the better hitters in the Marlins' system, Dean has a quick bat and barrels balls, but he will need to develop more power to make an impact as a left fielder.
Though he's blocked by star shortstop prospect Orlando Arcia in the Brewers' system, Rivera is a quality defender who enhanced his versatility by playing second base in the Minors and third base in the AFL this year. He also has been one of the hotter hitters in the Fall League, ranking sixth in batting (.372) and RBIs (10).
RHP Nick Burdi, C Mitch Garver, OF Adam Brett Walker II
Burdi and Walker are all about power. A reliever, Burdi can hit triple digits with his fastball and the low 90s with his slider. Walker has as much raw pop as anyone in the AFL and has led his league in homers -- and strikeouts -- in each of his four years as a pro. Garver hit 16 homers and slugged .481 in 127 at-bats in his first full season in 2014, but he left the yard just three times this year while his slugging percentage dropped nearly 150 points to .333.
First baseman Dominic Smith, who paces the Fall League in batting (.385) and on-base percentage (.519), would have represented the Mets, but he was scratched with a minor leg injury.
Signed for $3 million out of the Dominican Republic in 2009, Sanchez long has tantalized scouts with his raw power and arm strength and confounded them with his inconsistent hitting approach and receiving. He has been the top performer in the AFL, leading the league in homers (six), RBIs (17), extra-base hits (10), total bases (43) and slugging (.705). Hebert is a lefty reliever whose best attribute is his ability to command average stuff.
Manaea's $3.55 million bonus from the Royals set a supplemental first-round record in 2013, and he dominated Double-A after going to the Athletics in the Ben Zobrist trade this July. He does a good job of pitching off his fastball, which peaks at 96 and features deception, extension, plane and life. Nunez has the solid power and arm strength to profile at third base but may be better suited defensively for first base. Pinder is an offensive-minded infielder who has seen action at shortstop, second base and third base.
C Andrew Knapp, RHP Edubray Ramos
The first college catcher drafted in 2013 (second round), Knapp stands out most for his offense and exploded with a .360/.419/.631 line in 55 games after reaching Double-A. Ramos is a bullpen option who can miss bats with his mid-90s fastball and hard curveball.
C Reese McGuire, OF Austin Meadows, RHP Trevor Williams
High school picks who went in the top half of the first round of the 2013 Draft, Meadows (ninth overall) and McGuire (14th) are two of the best prospects in the AFL. Meadows is a center fielder with four potential plus tools, while McGuire is a gifted defender and a contact hitter who needs to add strength to do some damage at the plate. Williams was just acquired by the Bucs in a trade with the Marlins last month. His combination of stuff and pitchability could allow him to be a back-end starter in the big leagues in the near future.
3B Patrick Wisdom
Cards top prospect Alex Reyes, who is far and away the top pitching prospect in the Fall League, was originally on the roster but was removed the day before the game. Wisdom has standout defensive skills at the hot corner and the raw power to profile there, but he has struggled to produce consistently as a pro.
RHP Eric Yardley
A submarining reliever who thrives on deception and control, Yardley has progressed from independent ball to Double-A in two years.
The Giants made Arroyo a surprise first-round choice (25th overall) in 2013 because they believed in his bat, and he has hit .303 in the Minors and .367 in the AFL. He's showing hints of power, though his future defensive home is uncertain. Black throws consistently harder than anyone in the Minors and has topped out at 103 in Arizona, but he has a long medical history and won't reach his ceiling as a late-inning reliever if he can't stay healthy.
Arguably the best all-around college hitter in the 2013 Draft, in which the Mariners took him 12th overall, Peterson slumped in the AFL last year and again throughout the 2015 regular season. Taken from the Astros in the Rule 5 Draft at the 2014 Winter Meetings, Rollins is a reliever with a low-90s sinker. He missed much of this year while serving an 80-game suspension after a positive test for performance-enhancing drugs.
OF Jake Bauers, SS Daniel Robertson
Both of these advanced hitters were acquired via trade last winter. The key player in the deal that sent Zobrist from the Rays to the Athletics in January, Robertson is developing power but likely will move to second or third base. Part of the three-team Wil Myers /Steven Souza swap with the Nationals and Padres, Bauers is also growing into his pop and has an uncertain defensive future (left field or first base).
Baseball's consensus top prospect entering the 2013 season, Profar has missed most of the last two years after tearing a muscle in his throwing shoulder. The Rangers are protecting him by limiting him to DH duties in the AFL, but his bat speed and quickness look as good as ever.
LHP Chad Girodo, 1B Rowdy Tellez
Signed for a 30th-round record $850,000 in 2013, Tellez has huge left-handed power as well as a sound approach at the plate. Girodo is a sidearming reliever who fills the strike zone and destroys lefty hitters with his slider.
RHP Abel de los Santos
Acquired from the Rangers last December in a trade for Ross Detwiler, de los Santos saw his fastball jump to 92-96 mph when he became a full-time reliever in 2013.
Jim Callis is a reporter for MLB.com. Follow @jimcallisMLB on Twitter. This story was not subject to the approval of Major League Baseball or its clubs.