Astros set to open 2016 against Yanks in NY

Houston scheduled to face former NL Central foes in Interleague matchups

HOUSTON -- For only the sixth time in 35 years, the Astros will open a season on the road when they face the Yankees on April 4 at Yankee Stadium in the 2016 season opener. Major League Baseball released its tentative 2016 regular-season schedule on Tuesday.

The Astros will begin the season with three games in New York (April 4, 6-7) followed by three against the Brewers in Milwaukee (April 8-10) before returning to Houston for the April 11 home opener against the Royals at Minute Maid Park.

Tentative 2016 Astros schedule

In addition to the Brewers, the Astros will also see former National League Central foes when the Reds (June 17-19) and Cardinals (Aug. 16-17) return to Minute Maid Park for the first time since 2013. The Cubs (Sept. 9-11) will visit for the first time since '12. The Astros will play the Cardinals in St. Louis (June 14-15) and the Pirates at PNC Park (Aug. 22-24).

The Astros will face their in-state rivals, the Texas Rangers, 19 times, with the first of three home series scheduled for May 20-22. The other two three-game sets at Minute Maid Park will be August 5-7 and Sept. 12-14.

Additional highlights from the 2016 schedule include home matchups against the Red Sox (April 22-24), Yankees (July 25-27) and Blue Jays (Aug. 1-4).

Season tickets, group tickets, and individual-game suite rentals are on-sale now for the 2016 season. The purchase of 2016 full-season tickets also guarantees access to 2015 postseason ticket options. Fans can purchase tickets by calling the Astros ticket sales office at 1-800-Astros2 or by visiting www.astros.com.

Brian McTaggart is a reporter for MLB.com and writes an MLBlog, Tag's Lines. Follow @brianmctaggart on Twitter and listen to his podcast. This story was not subject to the approval of Major League Baseball or its clubs.