"It sounds like an MRI in the morning," manager Don Mattingly said. "We'll see where it is. I'd just be guessing at this point."
Puig reached on a grounder to shortstop Marcus Semien, reached for the bag, then pulled up a few steps later. After a brief discussion with vice president of medical services Stan Conte, Puig left and was replaced by pinch-runner Carl Crawford.
Puig missed the better part of two months earlier this year with a strained left hamstring.
Ken Gurnick is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.