The 25-year-old appeared in five games in his latest time with the Mariners, allowing six runs and 13 hits in 7 2/3 innings.
No corresponding move was announced Friday, but the Mariners will add another reliever to help a bullpen that had to soak up 5 2/3 innings in the loss when starter Mike Montgomery only lasted 2 1/3 frames.
"They're stretched out a little more than we'd have liked," manager Lloyd McClendon said after rookies David Rollins, Guaipe and Rob Rasmussen finished up the game. "All of them threw more pitches than we'd have liked. But given the situation -- first day on the road -- sometimes you've got to bite the bullet."
The primary choices to fill the vacancy would figure to be rookie Jose Ramirez, who was acquired from the Yankees two weeks ago in the Dustin Ackley trade, or veteran Danny Farquhar.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB, read his Mariners Musings blog, and listen to his podcast. This story was not subject to the approval of Major League Baseball or its clubs.